GM3 Labelled by NBD (Highly Pure)

Description

GM3 Labelled by NBD
Catalog number: MDP0887
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: 1219.3 g/mol
Supplied as: Ammonium Salt
Applications: fluoresence studies of GM3
Storage: -20°C
Keywords: O-(Acetamido-3,5-Dideoxy-D-Glycero-alpha-D-Galacto-2-Nonulopyranosylonic Acid)-(2-3)-O-beta-D-Galactopyranosyl-(1-4)-O-beta-D-Glucopyranosyl-(1-1)-(2S,3R,4E)-2-N-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl) Aminooctanamido-4-Octadecene-1,3-diol
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
Indication for Use:This product is for Research Use Only. This product is NOT for human or animal use.

References:
1: Zheng C, Terreni M, Sollogoub M, Zhang Y. Ganglioside GM3 and Its Role in
Cancer. Curr Med Chem. 2019;26(16):2933-2947.

2: Hakomori SI, Handa K. GM3 and cancer. Glycoconj J. 2015 Feb;32(1-2):1-8.

3: Inokuchi JI, Inamori KI, Kabayama K, Nagafuku M, Uemura S, Go S, Suzuki A,
Ohno I, Kanoh H, Shishido F. Biology of GM3 Ganglioside. Prog Mol Biol Transl
Sci. 2018;156:151-195.

4: Labrada M, Dorvignit D, Hevia G, Rodríguez-Zhurbenko N, Hernández AM, Vázquez
AM, Fernández LE. GM3(Neu5Gc) ganglioside: an evolution fixed neoantigen for
cancer immunotherapy. Semin Oncol. 2018 Jan;45(1-2):41-51.

5: Ao M, Wang K, Zhou X, Chen G, Zhou Y, Wei B, Shao W, Huang J, Liao H, Wang Z,
Sun Y, Zeng S, Chen Y. Exogenous GM3 ganglioside inhibits atherosclerosis via
multiple steps: A potential atheroprotective drug. Pharmacol Res. 2019
Oct;148:104445.

6: Hiraoka M, Ohkawa E, Abe A, Murata M, Go S, Inokuchi JI, Ohguro H. Visual
Function in Mice Lacking GM3 Synthase. Curr Eye Res. 2019 Jun;44(6):664-670.

7: Lipina C, Hundal HS. Ganglioside GM3 as a gatekeeper of obesity-associated
insulin resistance: Evidence and mechanisms. FEBS Lett. 2015 Oct
24;589(21):3221-7.

8: Kanoh H, Nitta T, Go S, Inamori KI, Veillon L, Nihei W, Fujii M, Kabayama K,
Shimoyama A, Fukase K, Ohto U, Shimizu T, Watanabe T, Shindo H, Aoki S, Sato K,
Nagasaki M, Yatomi Y, Komura N, Ando H, Ishida H, Kiso M, Natori Y, Yoshimura Y,
Zonca A, Cattaneo A, Letizia M, Ciampa M, Mauri L, Prinetti A, Sonnino S, Suzuki
A, Inokuchi JI. Homeostatic and pathogenic roles of GM3 ganglioside molecular
species in TLR4 signaling in obesity. EMBO J. 2020 Jun 17;39(12):e101732.

9: Tang FL, Wang J, Itokazu Y, Yu RK. Enhanced Susceptibility to
Chemoconvulsant-Induced Seizures in Ganglioside GM3 Synthase Knockout Mice. ASN
Neuro. 2020 Jan-Dec;12:1759091420938175.
10: Nishikawa M, Kurano M, Nitta T, Kanoh H, Inokuchi JI, Yatomi Y. Serum
GM3(d18:1-16:0) and GM3(d18:1-24:1) levels may be associated with lymphoma: An
exploratory study with haematological diseases. Sci Rep. 2019 Apr 19;9(1):6308.

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