Fluorophore 581/591 C11

Product Description

Fluorophore 581/591 C11
Catalog number: B2016204
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 504.42 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: BODIPY® 581/591 C11 (Lipid Peroxidation Sensor), C11
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Lyamzaev KG, Sumbatyan NV, Nesterenko AM, Kholina EG, Voskoboynikova N, Steinhoff HJ, Mulkidjanian AY, Chernyak BV. MitoCLox: A Novel Mitochondria-Targeted Fluorescent Probe for Tracing Lipid Peroxidation Oxid Med Cell Longev. 2019 Nov 13;2019:9710208.
2: Huang YX, Lin KH, Chiang JC, Chen WM, Lee H. Lysophosphatidic Acid Receptor 3 Activation Is Involved in the Regulation of Ferroptosis Int J Mol Sci. 2024 Feb 15;25(4):2315.
3: Forkink M, Basit F, Teixeira J, Swarts HG, Koopman WJH, Willems PHGM. Complex I and complex III inhibition specifically increase cytosolic hydrogen peroxide levels without inducing oxidative stress in HEK293 cells Redox Biol. 2015 Dec;6:607-616.
4: Martinez AM, Kim A, Yang WS. Detection of Ferroptosis by BODIPY™ 581/591 C11 Methods Mol Biol. 2020;2108:125-130.
5: Drummen GP, van Liebergen LC, Op den Kamp JA, Post JA. C11-BODIPY(581/591), an oxidation-sensitive fluorescent lipid peroxidation probe: (micro)spectroscopic characterization and validation of methodology Free Radic Biol Med. 2002 Aug 15;33(4):473-90.
6: Jiang Y, Zhao J, Li R, Liu Y, Zhou L, Wang C, Lv C, Gao L, Cui D. CircLRFN5 inhibits the progression of glioblastoma via PRRX2/GCH1 mediated ferroptosis J Exp Clin Cancer Res. 2022 Oct 20;41(1):307.
7: Gallelli MF, Allera C, Moncalvo E, Caldevilla M, Miragaya M, Monachesi N. Detection of lipid peroxidation in dog spermatozoa with the fluorescent dye C11-BODIPY(581/591) Reprod Domest Anim. 2022 Feb;57(2):196-199.
8: Du S, Shi H, Xiong L, Wang P, Shi Y. Canagliflozin mitigates ferroptosis and improves myocardial oxidative stress in mice with diabetic cardiomyopathy Front Endocrinol (Lausanne). 2022 Oct 14;13:1011669.
9: Mei H, Zhao L, Li W, Zheng Z, Tang D, Lu X, He Y. Inhibition of ferroptosis protects House Ear Institute-Organ of Corti 1 cells and cochlear hair cells from cisplatin-induced ototoxicity J Cell Mol Med. 2020 Oct;24(20):12065-12081.
10: Tai P, Chen X, Jia G, Chen G, Gong L, Cheng Y, Li Z, Wang H, Chen A, Zhang G, Zhu Y, Xiao M, Wang Z, Liu Y, Shan D, He D, Li M, Zhan T, Khan A, Li X, Zeng X, Li C, Ouyang D, Ai K, Chen X, Liu D, Liu Z, Wei D, Cao K. WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis J Transl Med. 2023 Nov 17;21(1):823.

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