Fluorogenic Calpain Substrate II

Description

Fluorogenic Calpain Substrate II
Catalog number: B2013433
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 mg
Molecular Weight or Concentration: 533.5 g/mol
Supplied as: Solid
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Calpain Substrate II, Fluorogenic, Suc-LY-AMC
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Campbell JS, Hallett MB. Active calpain in phagocytically competent human neutrophils: electroinjection of fluorogenic calpain substrate Biochem Biophys Res Commun. 2015 Feb 13;457(3):341-6.
2: Cardoso M, Oliveira D, Araujo H. Expression and Activity of Calpain A in Drosophila melanogaster Methods Mol Biol. 2019;1915:93-101.
3: Tompa P, Buzder-Lantos P, Tantos A, Farkas A, Szilágyi A, Bánóczi Z, Hudecz F, Friedrich P. On the sequential determinants of calpain cleavage J Biol Chem. 2004 May 14;279(20):20775-85.
4: Sergeev IN. Calcium signaling in cancer and vitamin D J Steroid Biochem Mol Biol. 2005 Oct;97(1-2):145-51.
5: Marzia M, Chiusaroli R, Neff L, Kim NY, Chishti AH, Baron R, Horne WC. Calpain is required for normal osteoclast function and is down-regulated by calcitonin J Biol Chem. 2006 Apr 7;281(14):9745-54.
6: Jennings S, Hallett MB. Single cell measurement of calpain activity in neutrophils reveals link to cytosolic Ca(2+) elevation and individual phagocytotic events Biochem Biophys Res Commun. 2019 Jul 12;515(1):163-168.
7: Schmaier AH, Bradford HN, Lundberg D, Farber A, Colman RW. Membrane expression of platelet calpain Blood. 1990 Mar 15;75(6):1273-81.
8: Ali MA, Stepanko A, Fan X, Holt A, Schulz R. Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity Biochem Biophys Res Commun. 2012 Jun 22;423(1):1-5.
9: De Maria A, Shi Y, Kumar NM, Bassnett S. Calpain expression and activity during lens fiber cell differentiation J Biol Chem. 2009 May 15;284(20):13542-13550.
10: Giguere CJ, Schnellmann RG. Limitations of SLLVY-AMC in calpain and proteasome measurements Biochem Biophys Res Commun. 2008 Jul 4;371(3):578-81.

Products Related to Fluorogenic Calpain Substrate II can be found at Substrates