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DSS (Highly Pure)

Original price was: $1,595.00.Current price is: $795.00.

Catalog Number: B2016367 (500 mg)
DSS (Highly Pure) is a high quality water insoluble, homobifunctional cross‐linker that reacts with primary amines through its two NHS (N‐hydroxysuccinimide )ester reactive groups. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

DSS (Highly Pure)
Catalog number: B2016367
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 500 mg
Molecular Weight or Concentration: 368.4
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: (Disuccinimidyl Suberate)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Jawhara S, Habib K, Maggiotto F, Pignede G, Vandekerckove P, Maes E, Dubuquoy L, Fontaine T, Guerardel Y, Poulain D. Modulation of intestinal inflammation by yeasts and cell wall extracts: strain dependence and unexpected anti-inflammatory role of glucan fractions PLoS One. 2012;7(7):e40648.
2: Di Saverio S, Gutierrez J, Avisar E. A retrospective review with long term follow up of 11,400 cases of pure mucinous breast carcinoma Breast Cancer Res Treat. 2008 Oct;111(3):541-7.
3: Gäbele E, Dostert K, Hofmann C, Wiest R, Schölmerich J, Hellerbrand C, Obermeier F. DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH J Hepatol. 2011 Dec;55(6):1391-9.
4: Hoffmann M, Schwertassek U, Seydel A, Weber K, Falk W, Hauschildt S, Lehmann J. A refined and translationally relevant model of chronic DSS colitis in BALB/c mice Lab Anim. 2018 Jun;52(3):240-252.
5: Zhang H, Zhuo S, Song D, Wang L, Gu J, Ma J, Gu Y, Ji M, Chen M, Guo Y. Icariin Inhibits Intestinal Inflammation of DSS-Induced Colitis Mice Through Modulating Intestinal Flora Abundance and Modulating p-p65/p65 Molecule Turk J Gastroenterol. 2021 Apr;32(4):382-392.
6: Zhao LP, Wu J, Quan W, Zhou Y, Hong H, Niu GY, Ting-Li, Huang SB, Qiao CM, Zhao WJ, Cui C, Shen YQ. DSS-induced acute colitis causes dysregulated tryptophan metabolism in brain: an involvement of gut microbiota J Nutr Biochem. 2023 May;115:109282.
7: Krause JL, Engelmann B, Schaepe SS, Rolle-Kampczyk U, Jehmlich N, Chang HD, Slanina U, Hoffman M, Lehmann J, Zenclussen AC, Herberth G, von Bergen M, Haange SB. DSS treatment does not affect murine colonic microbiota in absence of the host Gut Microbes. 2024 Jan-Dec;16(1):2297831.
8: Wirtz S, Neufert C, Weigmann B, Neurath MF. Chemically induced mouse models of intestinal inflammation Nat Protoc. 2007;2(3):541-6.
9: Wang M, Fan Z, Chen D, Yu B, He J, Yu J, Mao X, Huang Z, Luo Y, Luo J, Yan H, Zheng P. Dietary lactate supplementation can alleviate DSS-induced colitis in piglets Biomed Pharmacother. 2023 Feb;158:114148.
10: Huang M, Su J, Lou Z, Xie F, Pan W, Yang Z, Gu L, Xie F, Xu Z, Zhang L, Liu F, Lai H, Zhang L, Lin N. Application of a DSS colitis model in toxicologically assessing norisoboldine Toxicol Mech Methods. 2020 Feb;30(2):107-114.

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Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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