Diphtheria Toxin (unnicked) from Corynebacterium diphtheriae

Product Description

Diphtheria Toxin (unnicked) from Corynebacterium diphtheriae
Catalog number: B2017279
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: N/A
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −80°C
Keywords: N/A
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Parveen S, Bishai WR, Murphy JR. Corynebacterium diphtheriae: Diphtheria Toxin, the tox Operon, and Its Regulation by Fe2(+) Activation of apo-DtxR Microbiol Spectr. 2019 Jul;7(4):10.1128/microbiolspec.gpp3-0063-2019.
2: Weerasekera D, Möller J, Kraner ME, Azevedo Antunes C, Mattos-Guaraldi AL, Burkovski A. Beyond diphtheria toxin: cytotoxic proteins of Corynebacterium ulcerans and Corynebacterium diphtheriae Microbiology (Reading). 2019 Aug;165(8):876-890.
3: Fry NK, Pringle E, Newsholme W, Nicholls M, Stephenson J, Heathcock RT, Gower C, Lacy J, O’Boyle S, Litt DJ, Sheppard C, Groves N, D’Aeth J, Hopkins KL, Meunier D, De Zoysa A, Efstratiou A, Brown C, Chand M, Amirthalingam G. Household transmission of non-toxigenic diphtheria toxin gene-bearing Corynebacterium diphtheriae following a cluster of cutaneous cases in a specialist outpatient setting J Med Microbiol. 2023 Jun;72(6).
4: Greenfield L. Diphtheria toxin cloning and expression in Corynebacterium diphtheriae Targeted Diagn Ther. 1992;7:273-305.
5: Muthuirulandi Sethuvel DP, Subramanian N, Pragasam AK, Inbanathan FY, Gupta P, Johnson J, Sharma NC, Hemvani N, Veeraraghavan B, Anandan S, Sangal L. Insights to the diphtheria toxin encoding prophages amongst clinical isolates of Corynebacterium diphtheriae from India Indian J Med Microbiol. 2019 Jul-Sep;37(3):423-425.
6: Prygiel M, Mosiej E, Polak M, Krysztopa-Grzybowska K, Wdowiak K, Formińska K, Zasada AA. Challenges of Diphtheria Toxin Detection Toxins (Basel). 2024 May 26;16(6):245.
7: Pappenheimer AM Jr. Diphtheria toxin Annu Rev Biochem. 1977;46:69-94.
8: Doyle CJ, Mazins A, Graham RM, Fang NX, Smith HV, Jennison AV. Sequence Analysis of Toxin Gene-Bearing Corynebacterium diphtheriae Strains, Australia Emerg Infect Dis. 2017 Jan;23(1):105-107.
9: Ott L, Möller J, Burkovski A. Interactions between the Re-Emerging Pathogen Corynebacterium diphtheriae and Host Cells Int J Mol Sci. 2022 Mar 18;23(6):3298.
10: Suwanpatcharakul M, Pakdeecharoen C, Visuttitewin S, Pesirikan N, Chauvatcharin S, Pongtharangkul T. Process optimization for an industrial-scale production of Diphtheria toxin by Corynebacterium diphtheriae PW8 Biologicals. 2016 Nov;44(6):534-539.

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