DABCYL C2 Thiol-Reactive


Catalog Number: B2011418 (5 mg)

DABCYL C2 Thiol-Reactive is a high quality thiol-reactive building block for developing DABCYL-based FRET probes. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

In stock

SKU: B2011418 Categories: ,


DABCYL C2 Thiol-Reactive

Catalog number: B2011418
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 391.4 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: DABCYL C2 maleimide
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Szabó I, Illien F, Dókus LE, Yousef M, Baranyai Z, Bősze S, Ise S, Kawano K, Sagan S, Futaki S, Hudecz F, Bánóczi Z. Influence of the Dabcyl group on the cellular uptake of cationic peptides: short oligoarginines as efficient cell-penetrating peptides Amino Acids. 2021 Jul;53(7):1033-1049.
2: Mandal S, Mann G, Satish G, Brik A. Enhanced Live-Cell Delivery of Synthetic Proteins Assisted by Cell-Penetrating Peptides Fused to DABCYL Angew Chem Int Ed Engl. 2021 Mar 22;60(13):7333-7343.
3: Tyagi S, Kramer FR. Molecular beacons: probes that fluoresce upon hybridization Nat Biotechnol. 1996 Mar;14(3):303-8.
4: Kempf O, Kempf K, Schobert R, Bombarda E. Hydrodabcyl: A Superior Hydrophilic Alternative to the Dark Fluorescence Quencher Dabcyl Anal Chem. 2017 Nov 21;89(22):11893-11897.
5: Kawaguchi M, Ikegawa S, Ieda N, Nakagawa H. A Fluorescent Probe for Imaging Sirtuin Activity in Living Cells, Based on One-Step Cleavage of the Dabcyl Quencher Chembiochem. 2016 Oct 17;17(20):1961-1967.
6: Alvarado-González M, Gallo M, Lopez-Albarran P, Flores-Holguín N, Glossman-Mitnik D. DFT study of the interaction between the conjugated fluorescein and dabcyl system, using fluorescene quenching method J Mol Model. 2012 Sep;18(9):4113-20.
7: Harmon NM, Huang X, Hsiao CC, Wiemer AJ, Wiemer DF. Incorporation of a FRET pair within a phosphonate diester Bioorg Chem. 2021 Sep;114:105048.
8: Hofstetter O, Hofstetter H, Miron T, Wilchek M. The conversion of azo-quenchers to fluorophores Anal Biochem. 2019 Nov 15;585:113400.
9: Crisalli P, Hernández AR, Kool ET. Fluorescence quenchers for hydrazone and oxime orthogonal bioconjugation Bioconjug Chem. 2012 Sep 19;23(9):1969-80.
10: Leguizamon SC, Scott TF. Sequence-selective dynamic covalent assembly of information-bearing oligomers Nat Commun. 2020 Feb 7;11(1):784.

Products Related to
DABCYL C2 Thiol-Reactive can be found at

How to Order

1- Order online using our website’s automated shopping cart and checkout system (available 24/7).

2- Order by email: (we accept electronic PO, available 24/7).

3- Order by Fax: 1-858-437-9884 (available 24/7).

4- Order by phone: 1-858-900-3210 (6 am – 8 pm PST).

5- Order by Text/SMS: 1-858-900-3210 (6 am – 8 pm PST).