D-Leucine (Biotechnology Grade, High Purity)


Catalog Number: B2010184 (1 g)
D-Leucine is a high quality research product used as multipurpose amino acid for protein synthesis, reagent stabilization, preparation of culture media and more. Custom bulk orders of this product are available upon request.

In stock

SKU: B2010184 Category:


Catalog number: B2010184
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 1 g
pH: na
Supplied as: Ready-to-use
Appearance: White Powder
Applications: multipurpose amino acid for protein synthesis, reagent stabilization, preparation of culture media and more.
Storage: Room temperature
Keywords: (R)-2-Amino-4-methylpentanoic acid
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

1: Schoubben A, Vivani R, Paolantoni M, Perinelli DR, Gioiello A, Macchiarulo A,
Ricci M. D-leucine microparticles as an excipient to improve the aerosolization
performances of dry powders for inhalation. Eur J Pharm Sci. 2019 Mar

2: Koga R, Miyoshi Y, Sakaue H, Hamase K, Konno R. Mouse d-Amino-Acid Oxidase:
Distribution and Physiological Substrates. Front Mol Biosci. 2017 Dec 4;4:82.

3: Liska MG, Crowley MG, Tuazon JP, Borlongan CV. Neuroprotective and
neuroregenerative potential of pharmacologically-induced hypothermia with
D-alanine D-leucine enkephalin in brain injury. Neural Regen Res. 2018

4: Sasabe J, Suzuki M. Emerging Role of D-Amino Acid Metabolism in the Innate
Defense. Front Microbiol. 2018 May 9;9:933.

5: Hasegawa H, Matsukawa T, Shinohara Y, Konno R, Hashimoto T. Role of renal
D-amino-acid oxidase in pharmacokinetics of D-leucine. Am J Physiol Endocrinol
Metab. 2004 Jul;287(1):E160-5.

6: Zhang ZY, Ma N, Tao LJ, Gong XY, Ye WC, Wang L. Linear Peptides Containing
d-Leucine with Neuroprotective Activities from the Leech Whitmania pigra
Whitman. J Nat Prod. 2019 Aug 23;82(8):2349-2353.

7: Hasegawa H, Matsukawa T, Shinohara Y, Hashimoto T. Kinetics of sequential
metabolism from D-leucine to L-leucine via alpha-ketoisocaproic acid in rat.
Drug Metab Dispos. 2002 Dec;30(12):1436-40.

8: Hamase K, Inoue T, Morikawa A, Konno R, Zaitsu K. Determination of free
D-proline and D-leucine in the brains of mutant mice lacking D-amino acid
oxidase activity. Anal Biochem. 2001 Nov 15;298(2):253-8.

9: Sugimoto H, Kakehi M, Jinno F. Method development for the determination of D-
and L-isomers of leucine in human plasma by high-performance liquid
chromatography tandem mass spectrometry and its application to animal plasma
samples. Anal Bioanal Chem. 2015 Oct;407(26):7889-98.

Products Related to D-Leucine : Biochemical Buffers and Solutions

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