Collagenase Substrate (Highly Pure)

Product Description

Collagenase Substrate (Highly Pure)
Catalog number: B2012711
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 25 mg
Molecular Weight or Concentration: 588.6 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Z-Gly-Pro-Gly-Gly-Pro-Ala-OH
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: De Souza SJ, Pereira HM, Jacchieri S, Brentani RR. Collagen/collagenase interaction: does the enzyme mimic the conformation of its own substrate? FASEB J. 1996 Jun;10(8):927-30.
2: Ikeuchi T, Yasumoto M, Takita T, Tanaka K, Kusubata M, Hayashida O, Hattori S, Mizutani K, Mikami B, Yasukawa K. Crystal structure of Grimontia hollisae collagenase_provides insights into its novel substrate specificity toward collagen J Biol Chem. 2022 Aug;298(8):102109.
3: Leber TM, Balkwill FR. Zymography: a single-step staining method for quantitation of proteolytic activity on substrate gels Anal Biochem. 1997 Jun 15;249(1):24-8.
4: Bhattacharya S, Bhattacharya S, Gachhui R, Hazra S, Mukherjee J. U32 collagenase_from Pseudoalteromonas agarivorans NW4327: Activity, structure, substrate interactions and molecular dynamics simulations Int J Biol Macromol. 2019 Mar 1;124:635-650.
5: Tsu CA, Craik CS. Substrate recognition by recombinant serine collagenase 1 from Uca pugilator J Biol Chem. 1996 May 10;271(19):11563-70.
6: Al-Abdullah IH, Bagramyan K, Bilbao S, Qi M, Kalkum M. Fluorogenic Peptide Substrate for Quantification of Bacterial Enzyme Activities Sci Rep. 2017 Mar 13;7:44321.
7: Deng SJ, Bickett DM, Mitchell JL, Lambert MH, Blackburn RK, Carter HL 3rd, Neugebauer J, Pahel G, Weiner MP, Moss ML. Substrate specificity of human collagenase_3 assessed using a phage-displayed peptide library J Biol Chem. 2000 Oct 6;275(40):31422-7.
8: Saikumari YK, Balaram P. An internally quenched fluorescent substrate for collagenase Biopolymers. 2008;90(2):131-7.
9: Shima H, Inagaki A, Imura T, Yamagata Y, Watanabe K, Igarashi K, Goto M, Murayama K. Collagen V Is a Potential Substrate for Clostridial Collagenase G in Pancreatic Islet Isolation J Diabetes Res. 2016;2016:4396756.
10: Hasty KA, Jeffrey JJ, Hibbs MS, Welgus HG. The collagen substrate specificity of human neutrophil collagenase J Biol Chem. 1987 Jul 25;262(21):10048-52.

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