Cholic Acid (Biotechnology Grade)
Catalog Number: B2010069 (1 g)
Cholic Acid is a high quality research product used as bile acid produced in the liver and that facilitates fat absorption and cholesterol excretion. Due to its non-denaturing ionic detergent properties, it has several biochemical applications. Custom bulk orders of this product are available upon request.
Catalog number: B2010069
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 1 g
Supplied as: Ready-to-use
Appearance: White Powder
Applications: bile acid produced in the liver and that facilitates fat absorption and cholesterol excretion. Due to its non-denaturing ionic detergent properties, it has several biochemical applications.
Storage: Room temperature
Keywords: 3α,7α,12α-Trihydroxy-5β-cholanic acid, Cholanic acid
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.
1: Mandia D, Chaussenot A, Besson G, Lamari F, Castelnovo G, Curot J, Duval F,
Giral P, Lecerf JM, Roland D, Pierdet H, Douillard C, Nadjar Y. Cholic acid as a
treatment for cerebrotendinous xanthomatosis in adults. J Neurol. 2019
2: Han JY, Jeong HI, Park CW, Yoon J, Ko J, Nam SJ, Lim BK. Cholic Acid
Attenuates ER Stress-Induced Cell Death in Coxsackievirus-B3 Infection. J
Microbiol Biotechnol. 2018 Jan 28;28(1):109-114.
3: Heubi JE, Bove KE, Setchell KDR. Oral Cholic Acid Is Efficacious and Well
Tolerated in Patients With Bile Acid Synthesis and Zellweger Spectrum Disorders.
J Pediatr Gastroenterol Nutr. 2017 Sep;65(3):321-326.
4: Gonzales E, Matarazzo L, Franchi-Abella S, Dabadie A, Cohen J, Habes D,
Hillaire S, Guettier C, Taburet AM, Myara A, Jacquemin E. Cholic acid for
primary bile acid synthesis defects: a life-saving therapy allowing a favorable
outcome in adulthood. Orphanet J Rare Dis. 2018 Oct 29;13(1):190.
5: He XL, Wang LT, Gu XZ, Xiao JX, Qiu WW. A facile synthesis of ursodeoxycholic
acid and obeticholic acid from cholic acid. Steroids. 2018 Dec;140:173-178.
6: Dobson TE, Maxwell AR, Ramsubhag A. Antimicrobial cholic acid derivatives
from the Pitch Lake bacterium Bacillus amyloliquefaciens UWI-W23. Steroids. 2018
7: Pérez M, Sánchez M, García M, Patiño C LP, Blustein G, Palermo JA.
Antifouling activity of peracetylated cholic acid, a natural bile acid
derivative. Steroids. 2019 Sep;149:108414.
8: Fan L, Joseph JF, Durairaj P, Parr MK, Bureik M. Conversion of
chenodeoxycholic acid to cholic acid by human CYP8B1. Biol Chem. 2019 Apr
9: Gupta S, Thakur J, Pal S, Gupta R, Mishra D, Kumar S, Yadav K, Saini A,
Yavvari PS, Vedantham M, Singh A, Srivastava A, Prasad R, Bajaj A. CholicAcid-
Peptide Conjugates as Potent Antimicrobials against Interkingdom Polymicrobial
Biofilms. Antimicrob Agents Chemother. 2019 Oct 22;63(11):e00520-19.
10: Lu X, Fan Z. Determination of cholicacid in body fluids by β‑cyclodextrin-
modified N-doped carbon dot fluorescent probes. Spectrochim Acta A Mol Biomol
Spectrosc. 2019 Jun 5;216:342-348.
11: Zhang Z, Gu H, Zhao H, Liu Y, Fu S, Wang M, Zhou W, Xie Z, Yu H, Huang Z,
Gao X. Pharmacometabolomics in Endogenous Drugs: A New Approach for Predicting
the Individualized Pharmacokinetics of CholicAcid. J Proteome Res. 2017 Oct
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