CGP 42112

Product Description

CGP 42112
Catalog number: MDP0668
CAS Number: 203460-30-4
Sequence: Nic-Tyr-Lys(Z-Arg)-His-Pro-Ile (Nic-: Nicotinoyl, Z-: Benzyloxycarbonyl)
Amount: 500 ug
Molecular Weight: 1052 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Egidy G, Friedman J, Viswanathan M, Wahl LM, Saavedra JM. CGP-42112 partially activates human monocytes and reduces their stimulation by lipopolysaccharides Am J Physiol. 1997 Sep;273(3 Pt 1):C826-33.
2: Speth RC. [125I]CGP 42112 binding reveals differences between rat brain and adrenal AT2 receptor binding sites Regul Pept. 1993 Mar 19;44(2):189-97.
3: Jöhren O, Viswanathan M, Saavedra JM. Expression of non-angiotensin II -125I-CGP 42112 binding sites on activated microglia after kainic acid induced neurodegeneration Brain Res. 1995 Dec 8;702(1-2):153-61.
4: Heemskerk FM, Saavedra JM. Quantitative autoradiography of angiotensin II AT2 receptors with [125I]CGP 42112 Brain Res. 1995 Apr 17;677(1):29-38.
5: Hong KW, Rhim BY, Shin YW, Yoo SE. Characterization of PD 121981- and CGP 42112-induced unmasking of low concentration effects of angiotensin II in rabbit abdominal aorta J Pharmacol Exp Ther. 1994 Dec;271(3):1591-6.
6: Takekoshi K, Ishii K, Isobe K, Nanmoku T, Kawakami Y, Nakai T. Angiotensin-II subtype 2 receptor agonist (CGP-42112) inhibits catecholamine biosynthesis in cultured porcine adrenal medullary chromaffin cells Biochem Biophys Res Commun. 2000 Jun 7;272(2):544-50.
7: Viswanathan M, de Oliveira AM, Correa FM, Saavedra JM. Expression of a novel non-angiotensin II [125I]CGP 42112 binding site in healing wounds of the rat brain Brain Res. 1994 Sep 26;658(1-2):265-70.
8: Viswanathan M, de Oliveira AM, Wu RM, Chiueh CC, Saavedra JM. [125I]CGP 42112 reveals a non-angiotensin II binding site in 1-methyl-4-phenylpyridine (MPP+)-induced brain injury Cell Mol Neurobiol. 1994 Feb;14(1):99-104.
9: Takekoshi K, Ishii K, Kawakami Y, Isobe K, Nakai T. Activation of angiotensin II subtype 2 receptor induces catecholamine release in an extracellular Ca(2+)-dependent manner through a decrease of cyclic guanosine 3′,5′-monophosphate production in cultured porcine adrenal medullary chromaffin Cells Endocrinology. 2001 Jul;142(7):3075-86.
10: de Oliveira AM, Viswanathan M, Heemskerk FM, Correa FM, Saavedra JM. Specific, non-angiotensin, [125I]CGP 42112 binding sites in rat spleen macrophages Biochem Biophys Res Commun. 1994 Apr 29;200(2):1049-58.

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