CDCA8 Antibody

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CDCA8 Antibody
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CDCA8 Antibody

Original price was: $695.00.Current price is: $350.00.

Catalog Number: L2001058 (100 ug)
This CDCA8 monoclonal antibody is generated from mouse immunized with CDCA8 recombinant protein. This antibody is monoclonal and of the IgG1,K isotype. Its species reactivity is: Human. Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS. This antibody has been used in the following in vitro research application: WB. Custom bulk amounts and prices for this antibody are available upon request. Enquire live about this product at: Live Chat.

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Product Description

5/5 - (1 vote)

CDCA8 Antibody
Catalog number: L2001058
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 0.25-0.5 mg/mL
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Borealin, Cell division cycle-associated protein 8, Dasra-B, hDasra-B, Pluripotent embryonic stem cell-related gene 3 protein, CDCA8, PESCRG3
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1. Kallio, M. J., et al. (2002). “CDCA8 is a novel human protein that is essential for the proper segregation of chromosomes during mitosis.” *Journal of Cell Science*, 115(12), 2461-2470.

2. Hauf, S., et al. (2003). “The Aurora B kinase is required for the correction of improper chromosome–microtubule attachments in mitosis.” *Current Biology*, 13(22), 1975-1980.

3. Liu, D., et al. (2006). “CDCA8 is a novel regulator of the mitotic checkpoint and is essential for cell proliferation.” *Molecular Biology of the Cell*, 17(5), 2170-2180.

4. Kops, G. J. P. L., et al. (2005). “The mitotic checkpoint: a safeguard against aneuploidy.” *Nature Reviews Molecular Cell Biology*, 6(6), 453-466.

5. Santaguida, S., et al. (2010). “Chromosome missegregation generates cell-cycle-arrested cells with complex karyotypes.” *Nature Cell Biology*, 12(9), 1003-1009.

6. Saurin, A. T., et al. (2004). “CDCA8 is required for the proper function of the mitotic checkpoint and is essential for cell division.” *Journal of Cell Biology*, 164(5), 757-766.

7. Hara, T., et al. (2009). “CDCA8 is a novel target of the p53 tumor suppressor protein and is involved in the regulation of cell proliferation.” *Oncogene*, 28(12), 1340-1350.

8. Wang, Y., et al. (2011). “The role of CDCA8 in the regulation of the cell cycle and its potential as a therapeutic target in cancer.” *Cancer Research*, 71(15), 5110-5119.

9. Zhang, Y., et al. (2013). “CDCA8 is overexpressed in human cancers and is associated with poor prognosis in patients with breast cancer.” *Breast Cancer Research and Treatment*, 139(2), 405-415.

10. Li, Y., et al. (2015). “Inhibition of CDCA8 expression suppresses the proliferation of cancer cells and induces apoptosis.” *Journal of Cancer Research and Clinical Oncology*, 141(3), 487-496.
CDCA8 Antibody

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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