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Calmodulin Dependent Protein Kinase II 281-309

Original price was: $1,795.00.Current price is: $895.00.

Catalog Number: B2016561 (100 ug)
Calmodulin Dependent Protein Kinase II 281-309 is a high quality protein kinase that is activated by the binding of calcium-calmodulin. The sequence 281-309 likely refers to a specific region within the CaMKII protein. This region may be important for the regulation of the kinase activity or for its interaction with other proteins. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (2 votes)

Calmodulin Dependent Protein Kinase II 281-309
Catalog number: B2016561
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: N/A
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: Calmodulin Dependent Protein Kinase II 281-309
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Colbran RJ, Smith MK, Schworer CM, Fong YL, Soderling TR. Regulatory domain of calcium/calmodulin-dependent protein kinase II. Mechanism of inhibition and regulation by phosphorylation J Biol Chem. 1989 Mar 25;264(9):4800-4.
2: Ishida A, Fujisawa H. Stabilization of calmodulin-dependent protein kinase II through the autoinhibitory domain J Biol Chem. 1995 Feb 3;270(5):2163-70.
3: Colbran RJ, Fong YL, Schworer CM, Soderling TR. Regulatory interactions of the calmodulin-binding, inhibitory, and autophosphorylation domains of Ca2+/calmodulin-dependent protein kinase II J Biol Chem. 1988 Dec 5;263(34):18145-51.
4: Soderling TR, Fukunaga K, Rich DP, Fong YL, Smith K, Colbran RJ. Regulation of brain Ca2+/calmodulin-dependent protein kinase II Adv Second Messenger Phosphoprotein Res. 1990;24:206-11.
5: Rich DP, Colbran RJ, Schworer CM, Soderling TR. Regulatory properties of calcium/calmodulin-dependent protein kinase II in rat brain postsynaptic densities J Neurochem. 1989 Sep;53(3):807-16.
6: Fukunaga K, Miyamoto E, Soderling TR. Regulation of Ca2+/calmodulin-dependent protein kinase II by brain gangliosides J Neurochem. 1990 Jan;54(1):103-9.
7: Fong YL, Soderling TR. Studies on the regulatory domain of Ca2+/calmodulin-dependent protein kinase II. Functional analyses of arginine 283 using synthetic inhibitory peptides and site-directed mutagenesis of the alpha subunit J Biol Chem. 1990 Jul 5;265(19):11091-7.
8: Smyth JT, Abbott AL, Lee B, Sienaert I, Kasri NN, De Smedt H, Ducibella T, Missiaen L, Parys JB, Fissore RA. Inhibition of the inositol trisphosphate receptor of mouse eggs and A7r5 cells by KN-93 via a mechanism unrelated to Ca2+/calmodulin-dependent protein kinase II antagonism J Biol Chem. 2002 Sep 20;277(38):35061-70.
9: Carlier E, Dargent B, De Waard M, Couraud F. Na(+) channel regulation by calmodulin kinase II in rat cerebellar granule cells Biochem Biophys Res Commun. 2000 Aug 2;274(2):394-9.
10: Smith MK, Colbran RJ, Soderling TR. Specificities of autoinhibitory domain peptides for four protein kinases. Implications for intact cell studies of protein kinase function J Biol Chem. 1990 Feb 5;265(4):1837-40.

Products Related to Calmodulin Dependent Protein Kinase II 281-309 can be found at Enzymes

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (2 votes)

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