C12FDG (Highly Pure)

Product Description

C12FDG (Highly Pure)
Catalog number: B2016159
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 853.90 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: 5-Dodecanoylaminofluorescein Di-β-D-Galactopyranoside, Dodecanamide, N-[3′,6′-bis(β-D-galactopyranosyloxy)-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthen]-5-yl
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Debacq-Chainiaux F, Erusalimsky JD, Campisi J, Toussaint O. Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo Nat Protoc. 2009;4(12):1798-806.
2: Bernard M, Yang B, Migneault F, Turgeon J, Dieudé M, Olivier MA, Cardin GB, El-Diwany M, Underwood K, Rodier F, Hébert MJ. Autophagy drives fibroblast senescence through MTORC2 regulation Autophagy. 2020 Nov;16(11):2004-2016.
3: Okamoto Y, Monjushiro H, Fukumoto T, Watarai H. Measurement of hydrolysis kinetics of galactose-substituted fluorescein by beta-galactosidase at the toluene-water interface by spinning microtube fluorometry Anal Bioanal Chem. 2006 Aug;385(8):1430-8.
4: Waltz RA, Whitney KE, Duke VR, Kloser H, Huard C, Provencher MT, Philippon MJ, Bahney C, Godin JA, Huard J. A Systemic and Local Comparison of Senescence in an Acute Anterior Cruciate Ligament Injury-A Pilot Case Series Life (Basel). 2023 Jul 15;13(7):1567.
5: Beltzig L, Frumkina A, Schwarzenbach C, Kaina B. Cytotoxic, Genotoxic and Senolytic Potential of Native and Micellar Curcumin Nutrients. 2021 Jul 13;13(7):2385.
6: Fuhrmann-Stroissnigg H, Santiago FE, Grassi D, Ling Y, Niedernhofer LJ, Robbins PD. SA-β-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs J Vis Exp. 2019 Jun 28;(148).
7: Goy E, Martin N, Drullion C, Saas L, Molendi-Coste O, Pineau L, Dombrowicz D, Deruy E, Bauderlique-Le-Roy H, Samyn O, De Launoit Y, Abbadie C. Flow Cytometry-based Method for Efficient Sorting of Senescent Cells Bio Protoc. 2023 Apr 5;13(7):e4612.
8: Huang L, Shen Y, Liu C, Li C, Wang J. [Palbociclib induces cell cycle arrest and senescence of human renal tubular epithelial cells in vitro] Nan Fang Yi Ke Da Xue Xue Bao. 2020 Dec 30;40(12):1784-1792.
9: Díaz M, Pibuel M, Paglilla N, Poodts D, Álvarez E, Papademetrio DL, Hajos SE, Lompardía SL. 4-Methylumbelliferone induces antitumor effects independently of hyaluronan synthesis inhibition in human acute leukemia cell lines Life Sci. 2021 Dec 15;287:120065.
10: Parella KJ, Manhardt C, Capucilli D, Moyer B, Colegrove H, Moody KJ, Sleeper M, Banas A, Rebbaa A, Wolfe AJ. Fluorescence-Based Detection of Ferrous Iron in Senescent Cells Rejuvenation Res. 2021 Dec;24(6):456-463.

Products Related to C12FDG (Highly Pure) can be found at Substrates