Brij 58 Detergent (Biochemistry Grade)
Catalog Number: B2010159 (10 g)
Brij 58 is a high quality research product used as multipurpose nonionic surfactant with various applications in chemistry, biochemistry and clinical chemistry. Custom bulk orders of this product are available upon request.
Catalog number: B2010159
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 g
Supplied as: Ready-to-use
Applications: multipurpose nonionic surfactant with various applications in chemistry, biochemistry and clinical chemistry.
Storage: Room temperature
Keywords: Polyethylene glycol hexadecyl ether, Polyoxyethylene (20) cetyl ether
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.
1: Yue L, Yan Z, Li H, Liu X, Sun P. Brij-58, a potential injectable protein-
stabilizer used in therapeutic protein formulation. Eur J Pharm Biopharm. 2020
2: Roubalova L, Vosahlikova M, Brejchova J, Sykora J, Rudajev V, Svoboda P. High
Efficacy but Low Potency of δ-Opioid Receptor-G Protein Coupling in
Brij-58-Treated, Low-Density Plasma Membrane Fragments. PLoS One. 2015 Aug
3: Li X, Huang J, Yu G, Deng S. Photodestruction of BDE-99 in micellar solutions
of nonionic surfactants of Brij 35 and Brij 58. Chemosphere. 2010
4: Collins CA, Leslie ME, Peck SC, Heese A. Simplified Enrichment of Plasma
Membrane Proteins from Arabidopsis thaliana Seedlings Using Differential
Centrifugation and Brij-58 Treatment. Methods Mol Biol. 2017;1564:155-168.
5: Behzadipour M, Kluge M, Lüthje S. Changes in plasma membrane fluidity of corn
(Zea mays L.) roots after Brij 58 treatment. Protoplasma. 2001;217(1-3):65-9.
6: Nakagawa A, Tsujita T, Okuda H. Effect of Brj 58 on the hydrolysis of methyl
butyrate by lipase from Pseudomonas fluorescens. J Biochem. 1984
7: Mitra RK, Paul BK, Moulik SP. Phase behavior, interfacial composition and
thermodynamic properties of mixed surfactant (CTAB and Brj58) derived w/o
microemulsions with 1-butanol and 1-pentanol as cosurfactants and n-heptane and
n-decane as oils. J Colloid Interface Sci. 2006 Aug 15;300(2):755-64.
8: Casadei BR, Domingues CC, Clop EM, Couto VM, Perillo MA, de Paula E.
Molecular features of nonionic detergents involved in the binding kinetics and
solubilization efficiency, as studied in model (Langmuir films) and biological
(Erythrocytes) membranes. Colloids Surf B Biointerfaces. 2018 Jun 1;166:152-160.
9: Ridsdale JA, Clegg JS. Evidence for cooperativity of protein dissolution in
Brij 58 permeabilized L929 cells. J Cell Physiol. 1991 May;147(2):242-7.
10: Casadei BR, De Oliveira Carvalho P, Riske KA, Barbosa Rde M, De Paula E,
Domingues CC. Brij detergents reveal new aspects of membrane microdomain in
erythrocytes. Mol Membr Biol. 2014 Sep;31(6):195-205.
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