(Benzotriazol-1-yloxy)tripyrrolidinophosphonium Hexafluorophosphate

Product Description

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium Hexafluorophosphate
Catalog number: B2015866
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 250 mg
Molecular Weight or Concentration: 520.39
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: PyBOP®
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Fauconnot L, Robert F, Villard R, Dionisi F. Chemical synthesis and NMR characterization of structured polyunsaturated triacylglycerols Chem Phys Lipids. 2006 Feb;139(2):125-36.
3: Akula HK, Lakshman MK. Facile Modifications at the C4 Position of Pyrimidine Nucleosides via In Situ Amide Activation with 1H-Benzotriazol-1-yloxy-tris(dimethyl-amino)phosphonium Hexafluorophosphate Curr Protoc Nucleic Acid Chem. 2019 Mar;76(1):e73.
4: Akula HK, Kokatla H, Andrei G, Snoeck R, Schols D, Balzarini J, Yang L, Lakshman MK. Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products Org Biomol Chem. 2017 Feb 1;15(5):1130-1139.
5: Li P, Xu JC. (1H-benzotriazol-1-yloxy)-N,N-dimethylmethaniminium hexachloroantimonate (BOMI), a novel coupling reagent for solution and solid-phase peptide synthesis J Pept Res. 2000 Feb;55(2):110-9.
6: Bae S, Lakshman MK. O6-(benzotriazol-1-yl)inosine derivatives: easily synthesized, reactive nucleosides J Am Chem Soc. 2007 Jan 31;129(4):782-9.
7: Akula HK, Kokatla H, Andrei G, Snoeck R, Schols D, Balzarini J, Yang L, Lakshman MK. Correction: Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products Org Biomol Chem. 2017 Feb 1;15(5):1268.
8: Khandaker TA, Hess JD, Aguilera R, Andrei G, Snoeck R, Schols D, Pradhan P, Lakshman MK. Synthesis and Evaluations of “1,4-Triazolyl Combretacoumarins” and Desmethoxy Analogues European J Org Chem. 2019 Sep 8;2019(33):5610-5623.
9: Kokatla HP, Lakshman MK. Two-step, one-pot synthesis of inosine, guanosine, and 2′-deoxyguanosine O6-ethers via intermediate O6-(benzotriazol-1-yl) derivatives Curr Protoc Nucleic Acid Chem. 2012 Jun;Chapter 1:Unit1.26.
10: Bae S, Chaturvedi S, Lakshman MK. O6-(benzotriazol-1-yl)inosine derivatives for C6 modification of purine nucleosides Curr Protoc Nucleic Acid Chem. 2009 Mar;Chapter 1:Unit 1.22.

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