Arachidoyl Glycine (Highly Pure)

Product Description

Arachidoyl Glycine (Highly Pure)
Catalog number: B2013105
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 369.5 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: N-(1-oxoeicosyl)-glycine
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Console-Bram L, Ciuciu SM, Zhao P, Zipkin RE, Brailoiu E, Abood ME. N-arachidonoyl glycine, another endogenous agonist of GPR55 Biochem Biophys Res Commun. 2017 Sep 2;490(4):1389-1393.
2: Takenouchi R, Inoue K, Kambe Y, Miyata A. N-arachidonoyl glycine induces macrophage apoptosis via GPR18 Biochem Biophys Res Commun. 2012 Feb 10;418(2):366-71.
3: Baur R, Gertsch J, Sigel E. Do N-arachidonyl-glycine (NA-glycine) and 2-arachidonoyl glycerol (2-AG) share mode of action and the binding site on the β2 subunit of GABAA receptors? PeerJ. 2013 Sep 10;1:e149.
4: Parmar N, Ho WS. N-arachidonoyl glycine, an endogenous lipid that acts as a vasorelaxant via nitric oxide and large conductance calcium-activated potassium channels Br J Pharmacol. 2010 Jun;160(3):594-603.
5: Grabiec U, Hohmann T, Ghadban C, Rothgänger C, Wong D, Antonietti A, Groth T, Mackie K, Dehghani F. Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures Int J Mol Sci. 2019 Mar 13;20(6):1266.
6: Bondarenko AI, Drachuk K, Panasiuk O, Sagach V, Deak AT, Malli R, Graier WF. N-Arachidonoyl glycine suppresses Na⁺/Ca²⁺ exchanger-mediated Ca²⁺ entry into endothelial cells and activates BK(Ca) channels independently of GPCRs Br J Pharmacol. 2013 Jun;169(4):933-48.
7: McCue JM, Driscoll WJ, Mueller GP. Cytochrome c catalyzes the in vitro synthesis of arachidonoyl glycine Biochem Biophys Res Commun. 2008 Jan 11;365(2):322-7.
8: Al Suleimani YM, Al Mahruqi AS. The endogenous lipid N-arachidonoyl glycine is hypotensive and nitric oxide-cGMP-dependent vasorelaxant Eur J Pharmacol. 2017 Jan 5;794:209-215.
9: McHugh D, Hu SS, Rimmerman N, Juknat A, Vogel Z, Walker JM, Bradshaw HB. N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor BMC Neurosci. 2010 Mar 26;11:44.
10: McCue JM, Driscoll WJ, Mueller GP. In vitro synthesis of arachidonoyl amino acids by cytochrome c Prostaglandins Other Lipid Mediat. 2009 Nov;90(1-2):42-8.

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