all-trans Retinal (Highly Pure)

Product Description

all-trans Retinal (Highly Pure)
Catalog number: B2013076
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 mg
Molecular Weight or Concentration: 284.4 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Retinaldehyde, Vitamin A aldehyde
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Chen C, Chen J, Wang Y, Liu Z, Wu Y. Ferroptosis drives photoreceptor degeneration in mice with defects in all-trans-retinal clearance J Biol Chem. 2021 Jan-Jun;296:100187.
2: Maeda T, Golczak M, Maeda A. Retinal photodamage mediated by all_trans-retinal Photochem Photobiol. 2012 Nov-Dec;88(6):1309-19.
3: Sparrow JR, Wu Y, Kim CY, Zhou J. Phospholipid meets all_trans-retinal: the making of RPE bisretinoids J Lipid Res. 2010 Feb;51(2):247-61.
4: Li G, Hu Y, Pei S, Meng J, Wang J, Wang J, Yue S, Wang Z, Wang S, Liu X, Weng Y, Peng X, Zhao Q. Excited-state dynamics of all_trans protonated retinal Schiff base in CRABPII-based rhodopsin mimics Biophys J. 2022 Nov 1;121(21):4109-4118.
5: Masutomi K, Chen C, Nakatani K, Koutalos Y. All-trans retinal mediates light-induced oxidation in single living rod photoreceptors Photochem Photobiol. 2012 Nov-Dec;88(6):1356-61.
6: Chen C, Kono M, Koutalos Y. Photooxidation mediated by 11-cis and all_trans retinal in single isolated mouse rod photoreceptors Photochem Photobiol Sci. 2020 Oct 14;19(10):1300-1307.
7: Nagata T, Koyanagi M, Lucas R, Terakita A. An all_trans-retinal-binding opsin peropsin as a potential dark-active and light-inactivated G protein-coupled receptor Sci Rep. 2018 Feb 23;8(1):3535.
8: Boyer NP, Thompson DA, Koutalos Y. Relative Contributions of All_Trans and 11-Cis Retinal to Formation of Lipofuscin and A2E Accumulating in Mouse Retinal Pigment Epithelium Invest Ophthalmol Vis Sci. 2021 Feb 1;62(2):1.
9: Gao Z, Liao Y, Chen C, Liao C, He D, Chen J, Ma J, Liu Z, Wu Y. Conversion of all-trans-retinal into all_trans-retinal dimer reflects an alternative metabolic/antidotal pathway of all-trans-retinal in the retina J Biol Chem. 2018 Sep 14;293(37):14507-14519.
10: Chen H, Namkung MJ, Juchau MR. Biotransformation of all-trans-retinol and all-trans-retinal to all-trans-retinoic acid in rat conceptal homogenates Biochem Pharmacol. 1995 Oct 12;50(8):1257-64.

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