α-Defensin-6 (Human)
Original price was: $1,595.00.$725.00Current price is: $725.00.
Catalog number: MDP0816 (0.1 mg)
α-Defensin-6 (Human) is a synthetic peptide consisting of the sequence: Ala-Phe-Thr-Cys-His-Cys-Arg-Arg-Ser-Cys-Tyr-Ser-Thr-Glu-Tyr-Ser-Tyr-Gly-Thr-Cys-Thr-Val-Met-Gly-Ile-Asn-His-Arg-Phe-Cys-Cys-Leu (Disulfide bonds between Cys4-Cys31, Cys6-Cys20, and Cys10-Cys30). The molecular weight of this peptide is 3708.2 g/mol. This product is for in vitro research use only. This product is not for human or animal use. Custom bulk orders of this product are available upon request.
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Product Description
α-Defensin-6 (Human)
Catalog number: MDP0816
Amount: 0.1 mg
Name: Ala-Phe-Thr-Cys-His-Cys-Arg-Arg-Ser-Cys-Tyr-Ser-Thr-Glu-Tyr-Ser-Tyr-Gly-Thr-Cys-Thr-Val-Met-Gly-Ile-Asn-His-Arg-Phe-Cys-Cys-Leu (Disulfide bonds between Cys4-Cys31, Cys6-Cys20, and Cys10-Cys30)
Other name(s): α-Defensin-6 (Human)
Molecular Formula: C156H228N46O46S7
Molecular Mass: 3708.2 g/mol
CAS #: N/A
Storage Temperature: -20℃
References:
1: Hayashi R, Tsuchiya K, Fukushima K, Horita N, Hibiya S, Kitagaki K, Negi M, Itoh E, Akashi T, Eishi Y, Okada E, Araki A, Ohtsuka K, Fukuda S, Ohno H, Okamoto R, Nakamura T, Tanaka S, Chayama K, Watanabe M. Reduced Human α-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn’s Disease Inflamm Bowel Dis. 2016 May;22(5):1119-28.
2: Chakraborty S, Chatterjee R, Chakravortty D. Evolving and assembling to pierce through: Evolutionary and structural aspects of antimicrobial peptides Comput Struct Biotechnol J. 2022 May 10;20:2247-2258.
3: Wang A, Su Y, Wang S, Shen M, Chen F, Chen M, Ran X, Cheng T, Wang J. High efficiency preparation of bioactive human alpha-defensin 6 in Escherichia coli Origami(DE3)pLysS by soluble fusion expression Appl Microbiol Biotechnol. 2010 Aug;87(5):1935-42.
4: Mathew B, Nagaraj R. Antimicrobial activity of human α-defensin 6 analogs: insights into the physico-chemical reasons behind weak bactericidal activity of HD6 in vitro J Pept Sci. 2015 Nov;21(11):811-8.
5: Wyatt MC, Beswick AD, Kunutsor SK, Wilson MJ, Whitehouse MR, Blom AW. The Alpha-Defensin Immunoassay and Leukocyte Esterase Colorimetric Strip Test for the Diagnosis of Periprosthetic Infection: A Systematic Review and Meta-Analysis J Bone Joint Surg Am. 2016 Jun 15;98(12):992-1000.
6: Tang Y, Zhang D, Gong X, Zheng J. Repurposing of intestinal defensins as multi-target, dual-function amyloid inhibitors via cross-seeding Chem Sci. 2022 May 20;13(24):7143-7156.
7: Su X, Jin M, Xu C, Gao Y, Yang Y, Qi H, Zhang Q, Yang X, Ya W, Zhang Y, Yang R. FABP4 in Paneth cells regulates antimicrobial protein expression to reprogram gut microbiota Gut Microbes. 2022 Jan-Dec;14(1):2139978.
8: Li X, Ma H, Sun Y, Li T, Wang C, Zheng H, Chen G, Du G, Ji G, Yang H, Xiao W, Qiu Y. Effects of fecal stream deprivation on human intestinal barrier after loop ileostomy J Gastroenterol Hepatol. 2022 Jun;37(6):1119-1130.
9: Pereira NS, Queiroga TBD, da Silva DD, Nascimento MSL, Andrade CM, Souto JT, Ricci MF, Arantes RME, Zamboni DS, Chiari E, Câmara ACJD, Galvão LMDC, Guedes PMM. NOD2 receptor is crucial for protecting against the digestive form of Chagas disease PLoS Negl Trop Dis. 2020 Sep 28;14(9):e0008667.
10: Paulsen FP, Pufe T, Schaudig U, Held-Feindt J, Lehmann J, Schröder JM, Tillmann BN. Detection of natural peptide antibiotics in human nasolacrimal ducts Invest Ophthalmol Vis Sci. 2001 Sep;42(10):2157-63.
Products Related to α-Defensin-6 (Human) can be found at Peptides
Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |
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