5-Nitro-DL-tryptophan (Highly Pure)

Product Description

5-Nitro-DL-tryptophan (Highly Pure)
Catalog number: B2016218
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 250 mg
Molecular Weight or Concentration: 249.23 g/mol
Supplied as: Solution When Dissolved
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: DL-2-Amino-3-(5-nitroindolyl)propionic acid; H-5-Nitro-DL-Trp-OH
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Choi JS, Kim CS, Berdis A. Inhibition of Translesion DNA Synthesis as a Novel Therapeutic Strategy to Treat Brain Cancer Cancer Res. 2018 Feb 15;78(4):1083-1096.
2: Choi JS, Berdis A. Artificial Nucleosides as Diagnostic Probes to Measure Translesion DNA Synthesis Methods Mol Biol. 2019;1973:237-249.
3: Motea EA, Lee I, Berdis AJ. A non-natural nucleoside with combined therapeutic and diagnostic activities against leukemia ACS Chem Biol. 2012 Jun 15;7(6):988-98.
4: Motea EA, Lee I, Berdis AJ. Development of a ‘clickable’ non-natural nucleotide to visualize the replication of non-instructional DNA lesions Nucleic Acids Res. 2012 Mar;40(5):2357-67.
5: Reineks EZ, Berdis AJ. Evaluating the contribution of base stacking during translesion DNA replication Biochemistry. 2004 Jan 20;43(2):393-404.
6: Ahmad MF, Wan Q, Jha S, Motea E, Berdis A, Dealwis C. Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase Mol Cancer Ther. 2012 Oct;11(10):2077-86.
7: Wu X, Ma X, Zhong Y, Chen W, Xu M, Zhang H, Wang L, Tu X, Han Z, Zhao W, Wu Z, Moschos SJ, Li Z. Development of [(18)F]F-5-OMe-Tryptophans through Photoredox Radiofluorination: A New Method to Access Tryptophan-Based PET Agents J Med Chem. 2023 Mar 9;66(5):3262-3272.
8: Shirmovsky SE, Chizhov AV. Modeling of the entangled states transfer processes in microtubule tryptophan system Biosystems. 2023 Sep;231:104967.
9: Zou Y, Yu L, Fang X, Zheng Y, Yang Y, Wang C. Position-coded multivalent peptide-peptide interactions revealed by tryptophan-scanning mutagenesis J Pept Sci. 2020 Sep;26(9):e3273.
10: Richaud AD, Mandal S, Das A, Roche SP. Tunable CH/π Interactions within a Tryptophan Zipper Motif to Stabilize the Fold of Long β-Hairpin Peptides ACS Chem Biol. 2023 Dec 15;18(12):2555-2563.

Products Related to 5-Nitro-DL-tryptophan (Highly Pure) can be found at Chemicals