5-Methoxy-2-methylindole (Highly Pure)

Product Description

5-Methoxy-2-methylindole (Highly Pure)
Catalog number: B2016304
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 250 mg
Molecular Weight or Concentration: 161.21 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: 5-Methoxy-2-methylindole
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Indomethacin 2021 Jan 18. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–.
2: Tanaka I, Yoshizumi H, Tanaka Y, Takeda S, Kamei C, Nakaya N, Kitazumi K, Tagami H, Tasaka K. Pharmacological profiles of 2-carboxyphenyl-1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetate and 2-[(2-carboxyphenoxy)-carbonyl]phenyl-1-(4-chlorobenzoyl)-5-meth oxy-2- methylindole-3-acetate, new antiinflammatory agents Arzneimittelforschung. 1986 Apr;36(4):703-9.
3: WINTER CA, RISLEY EA, NUSS GW. ANTI-INFLAMMATORY AND ANTIPYRETIC ACTIVITIES OF INDOMETHACIN, 1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID J Pharmacol Exp Ther. 1963 Sep;141:369-76.
4: Paris GY, Garmaise DL, Cimon DG, Swett L, Carter GW, Young P. Glycerides as prodrugs. 3. Synthesis and antiinflammatory activity of [1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetyl]glycerides (indomethacin glycerides) J Med Chem. 1980 Jan;23(1):9-13.
5: O’Hara E, Seymour J. Inducing metamorphosis in the irukandji jellyfish Carukia barnesi Sci Rep. 2022 May 31;12(1):9052.
6: Giordano M, Capelli L, Chianese U. The therapeutic activity of 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid monohydrate glucosamide in rheumatoid arthritis (double blind trial) Arzneimittelforschung. 1975 Mar;25(3):435-7.
7: Ueda I, Ishii K, Arai H, Ikeda S, Hitomi Y, Hatanaka M. Design, synthesis and antiinflammatory activity of a new indomethacin ester. 2-[N-[3-(3-(piperidinomethyl)phenoxy)propyl]carbamoylmethylthio]ethyl 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-indole-3-acetate Chem Pharm Bull (Tokyo). 1991 Mar;39(3):679-84.
8: Helleberg L. Clinical Pharmacokinetics of indomethacin Clin Pharmacokinet. 1981 Jul-Aug;6(4):245-58.
9: Kistenmacher TJ, Marsh RE. Crystal and molecular structure of an antiinflammatory agent, indomethacin, 1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetic acid J Am Chem Soc. 1972 Feb 23;94(4):1340-5.
10: Helm RR, Dunn CW. Indoles induce metamorphosis in a broad diversity of jellyfish, but not in a crown jelly (Coronatae) PLoS One. 2017 Dec 27;12(12):e0188601.

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