5-Fluoro-L-tryptophan Monohydrate (Highly Pure)

Product Description

5-Fluoro-L-tryptophan Monohydrate (Highly Pure)
Catalog number: B2016227
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: 240.24 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: H-5-Fluoro-Trp-OH
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Eriksson O, Selvaraju R, Borg B, Asplund V, Estrada S, Antoni G. 5-Fluoro-[β-¹¹C]-L-tryptophan is a functional analogue of 5-hydroxy-[β-¹¹C]-L-tryptophan in vitro but not in vivo Nucl Med Biol. 2013 May;40(4):567-75.
2: Ferrer L, Elsaraf M, Mindt M, Wendisch VF. l-Serine Biosensor-Controlled Fermentative Production of l-Tryptophan Derivatives by Corynebacterium glutamicum Biology (Basel). 2022 May 13;11(5):744.
3: Tang T, Gill HS, Ogasawara A, Tinianow JN, Vanderbilt AN, Williams SP, Hatzivassiliou G, White S, Sandoval W, DeMent K, Wong M, Marik J. Preparation and evaluation of L- and D-5-[(18)F]fluorotryptophan as PET imaging probes for indoleamine and tryptophan 2,3-dioxygenases Nucl Med Biol. 2017 Aug;51:10-17.
4: Pfefferkorn CM, Lee JC. 5-fluoro-D,L-tryptophan as a dual NMR and fluorescent probe of α-synuclein Methods Mol Biol. 2012;895:197-209.
5: Miles EW, Phillips RS, Yeh HJ, Cohen LA. Isomerization of (3S)-2,3-dihydro-5-fluoro-L-tryptophan and of 5-fluoro-L-tryptophan catalyzed by tryptophan synthase: studies using fluorine-19 nuclear magnetic resonance and difference spectroscopy Biochemistry. 1986 Jul 29;25(15):4240-9.
6: Aymard N, Honore P, Carbuccia I. Determination of 5-hydroxytryptamine and tryptophan by liquid chromatography in whole blood. Its interest for the exploration of mental disorders Prog Neuropsychopharmacol Biol Psychiatry. 1994 Jan;18(1):77-86.
7: Phillips RS. Reactions of O-acyl-L-serines with tryptophanase, tyrosine phenol-lyase, and tryptophan synthase Arch Biochem Biophys. 1987 Jul;256(1):302-10.
8: Rosenfeld H, Feigelson P. Product induction in Pseudomonas acidovorans of a permease system which transports L-tryptophan J Bacteriol. 1969 Feb;97(2):705-14.
9: Brady FO, Feigelson P. The oxygenated complexes of the two catalytically active oxidation-reduction states of L-tryptophan-2,3-dioxygenase J Biol Chem. 1975 Jul 10;250(13):5041-8.
10: Taub M, Englesberg E. Isolation and characterization of 5-fluorotryptophan-resistant mutants with altered L-tryptophan transport Somatic Cell Genet. 1976 Sep;2(5):441-52.

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