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360 MMP FRET Substrate I

Original price was: $1,795.00.Current price is: $895.00.

Catalog Number: B2019473 (2 m g)
360 MMP FRET Substrate I is a biochemical compound used in research to study matrix metalloproteinases (MMPs). It emits fluorescence when cleaved by these enzymes, allowing researchers to monitor MMP activity in real-time and gain insights into various biological processes. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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Product Description

5/5 - (1 vote)

360 MMP FRET Substrate I
Catalog number: B2019473
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 2 m g
Molecular Weight or Concentration: 977.1
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Dnp-PLGLWAr-NH2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Kondo MY, Gouvea IE, Okamoto DN, Santos JA, Souccar C, Oda K, Juliano L, Juliano MA. Analysis of catalytic properties of tripeptidyl peptidase I (TTP-I), a serine carboxyl lysosomal protease, and its detection in tissue extracts using selective FRET peptide substrate Peptides. 2016 Feb;76:80-6.
2: Wu K, Ching K, Chong RA, Pan ZQ. A new FRET-based platform to track substrate ubiquitination by fluorescence J Biol Chem. 2021 Jan-Jun;296:100230.
3: Mohamed ZH, Rhein C, Saied EM, Kornhuber J, Arenz C. FRET probes for measuring sphingolipid metabolizing enzyme activity Chem Phys Lipids. 2018 Nov;216:152-161.
4: Kitamura S, Wolan DW. Probing substrate recognition of bacterial lipoprotein signal peptidase using FRET reporters FEBS Lett. 2018 Jul;592(13):2289-2296.
5: McCartney CE, MacLeod JA, Greer PA, Davies PL. An easy-to-use FRET protein substrate to detect calpain cleavage in vitro and in vivo Biochim Biophys Acta Mol Cell Res. 2018 Feb;1865(2):221-230.
6: El-Khoury R, Roman M, Assi HA, Moye AL, Bryan TM, Damha MJ. Telomeric i-motifs and C-strands inhibit parallel G-quadruplex extension by telomerase Nucleic Acids Res. 2023 Oct 27;51(19):10395-10410.
7: Rashid F, Harris PD, Zaher MS, Sobhy MA, Joudeh LI, Yan C, Piwonski H, Tsutakawa SE, Ivanov I, Tainer JA, Habuchi S, Hamdan SM. Single-molecule FRET unveils induced-fit mechanism for substrate selectivity in flap endonuclease 1 Elife. 2017 Feb 23;6:e21884.
8: Hamers D, van Voorst Vader L, Borst JW, Goedhart J. Development of FRET biosensors for mammalian and plant systems Protoplasma. 2014 Mar;251(2):333-47.
9: Li IT, Pham E, Chiang JJ, Truong K. FRET evidence that an isoform of caspase-7 binds but does not cleave its substrate Biochem Biophys Res Commun. 2008 Aug 22;373(2):325-9.
10: Rosenbach H, Steger G. Fluorescence-Based Kinetic Measurements for RNA-Cleaving DNAzymes Methods Mol Biol. 2022;2439:65-77.

Products Related to 360 MMP FRET Substrate I can be found at Substrates

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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