25-NBD Cholesterol
Original price was: $1,595.00.$795.00Current price is: $795.00.
Catalog Number: B2018559 (1 mg)
25-NBD cholesterol is a fluorescent derivative of cholesterol used in research to study cholesterol metabolism and trafficking in cells. The NBD group allows for easy detection and visualization in biological samples, tracking cholesterol movement and distribution in cells for studying cellular processes. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
Live enquiry about this product via Text/SMS: 1-858-900-3210.
In stock
Product Description
25-NBD Cholesterol
Catalog number: B2018559
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 564.759
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: 25-[N-[(7-nitro-2-1,3-benzoxadiazol-4-yl)methyl]amino]-27-norcholesterol
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Ostašov P, Sýkora J, Brejchová J, Olżyńska A, Hof M, Svoboda P. FLIM studies of 22- and 25-NBD-cholesterol in living HEK293 cells: plasma membrane change induced by cholesterol depletion Chem Phys Lipids. 2013 Feb-Mar;167-168:62-9.
2: Robalo JR, Ramalho JP, Loura LM. NBD-labeled cholesterol analogues in phospholipid bilayers: insights from molecular dynamics J Phys Chem B. 2013 Nov 7;117(44):13731-42.
3: Faletrov YV, Frolova NS, Hlushko HV, Rudaya EV, Edimecheva IP, Mauersberger S, Shkumatov VM. Evaluation of the fluorescent probes Nile Red and 25-NBD-cholesterol as substrates for steroid-converting oxidoreductases using pure enzymes and microorganisms FEBS J. 2013 Jul;280(13):3109-19.
4: Tugaeva KV, Faletrov YV, Allakhverdiev ES, Shkumatov VM, Maksimov EG, Sluchanko NN. Effect of the NBD-group position on interaction of fluorescently-labeled cholesterol analogues with human steroidogenic acute regulatory protein STARD1 Biochem Biophys Res Commun. 2018 Feb 26;497(1):58-64.
5: Pucadyil TJ, Mukherjee S, Chattopadhyay A. Organization and dynamics of NBD-labeled lipids in membranes analyzed by fluorescence recovery after photobleaching J Phys Chem B. 2007 Mar 1;111(8):1975-83.
6: Tesnière C, Pradal M, Legras JL. Sterol uptake analysis in Saccharomyces and non-Saccharomyces wine yeast species FEMS Yeast Res. 2021 Apr 7;21(3):foab020.
7: Ujčíková H, Brejchová J, Vošahlíková M, Kagan D, Dlouhá K, Sýkora J, Merta L, Drastichová Z, Novotný J, Ostašov P, Roubalová L, Parenti M, Hof M, Svoboda P. Opioid-receptor (OR) signaling cascades in rat cerebral cortex and model cell lines: the role of plasma membrane structure Physiol Res. 2014;63(Suppl 1):S165-76.
8: Mukherjee S, Zha X, Tabas I, Maxfield FR. Cholesterol distribution in living cells: fluorescence imaging using dehydroergosterol as a fluorescent cholesterol analog Biophys J. 1998 Oct;75(4):1915-25.
9: Liu S, Sui Q, Zhao Y, Chang X. Lonicera caerulea Berry Polyphenols Activate SIRT1, Enhancing Inhibition of Raw264.7 Macrophage Foam Cell Formation and Promoting Cholesterol Efflux J Agric Food Chem. 2019 Jun 26;67(25):7157-7166.
10: Shi F, Yang F, He X, Zhang Y, Wu S, Li M, Zhang Y, Di W, Dou J, Gu N. Inhibitory effect of epirubicin-loaded lipid microbubbles with conjugated anti-ABCG2 antibody combined with therapeutic ultrasound on multiple myeloma cancer stem cells J Drug Target. 2016;24(1):34-46.
Products Related to 25-NBD Cholesterol can be found at Lipids
Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |
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