12(S)-Hydroxy-(5Z,8E,10E)-heptadecatrienoic Acid

Product Description

12(S)-Hydroxy-(5Z,8E,10E)-heptadecatrienoic Acid
Catalog number: B2018104
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 μg
Molecular Weight or Concentration: 280.4
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20℃
Keywords: 12(S)-HHT
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: John H, Schlegel W. Thermodynamic and structural characterization of cis-trans isomerization of 12-(S)-hydroxy-(5Z, 8E, 10E)-heptadecatrienoic acid by high-performance liquid chromatography and gaschromatography-mass spectrometry Chem Phys Lipids. 1998 Oct;95(2):181-8.
2: Hofmann U, Seefried S, Meese CO, Mettang T, Hübel E, Kuhlmann U. Measurement of 12(S)-hydroxy-5Z,8E,10E-heptadecatrienoic acid and its metabolite 12-oxo-5Z,8E,10E-heptadecatrienoic acid in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry Anal Biochem. 1990 Sep;189(2):244-8.
3: Wang P, Ma J, Li W, Wang Q, Xiao Y, Jiang Y, Gu X, Wu Y, Dong S, Guo H, Li M. Profiling the metabolome of uterine fluid for early detection of ovarian cancer Cell Rep Med. 2023 Jun 20;4(6):101061.
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5: Agins AP, Thomas MJ, Edmonds CG, McCloskey JA. Identification of 12-keto-5,8,10-heptadecatrienoic acid as an arachidonic acid metabolite produced by human HL-60 leukemia cells Biochem Pharmacol. 1987 Jun 1;36(11):1799-805.
6: Okuno T, Yokomizo T. Metabolism and biological functions of 12(S)-hydroxyheptadeca-5Z,8E,10E-trienoic acid Prostaglandins Other Lipid Mediat. 2021 Feb;152:106502.
7: Vincent JE, Zijlstra FJ, van Vliet H. Determination of the formation of thromboxane B2 (TxB2), 12L-hydroxy-5,8,10 heptadecatrienoic acid (HHT) and 12L-hydroxy-5,8,10,14 eicosatrienoic acid (HETE) from arachidonic acid and of the TxB2 :HHT, TxB2 :HETE and (TxB2 +HHT) :HETE ratio in human platelets. Possible use in diagnostic purposes Prostaglandins Med. 1980 Aug;5(2):79-84.
8: Hofmann U, Seefried S, Meese CO, Mettang T, Hübel E, Kuhlmann U. Measurement of 12(S)-hydroxy-5Z,8E,10E-heptadecatrienoic acid and its metabolite 12-oxo-5Z,8E,10E-heptadecatrienoic acid in human plasma by gas chromatography/negative ion chemical ionization mass spectrometry Anal Biochem. 1990 Sep;189(2):244-8.
9: Saeki K, Yokomizo T. Identification, signaling, and functions of LTB(4) receptors Semin Immunol. 2017 Oct;33:30-36.
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