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1-oleoyl-sn-glycero-2,3-cyclic-phosphate, 18:1 Cyclic LPA

Original price was: $1,595.00.Current price is: $795.00.

Catalog Number: B2019252 (1 mg)
1-oleoyl-sn-glycero-2,3-cyclic-phosphate, or 18:1 cyclic LPA, is a phospholipid with a cyclic phosphate group derived from oleic acid. Its unique cyclic structure affects interactions with receptors and enzymes, influencing biological effects. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

1-oleoyl-sn-glycero-2,3-cyclic-phosphate, 18:1 Cyclic LPA
Catalog number: B2019252
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 435.275
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: 18:1 Cyclic LPA
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Jongsma M, Matas-Rico E, Rzadkowski A, Jalink K, Moolenaar WH. LPA is a chemorepellent for B16 melanoma cells: action through the cAMP-elevating LPA5 receptor PLoS One. 2011;6(12):e29260.
2: Morales-Lázaro SL, Serrano-Flores B, Llorente I, Hernández-García E, González-Ramírez R, Banerjee S, Miller D, Gududuru V, Fells J, Norman D, Tigyi G, Escalante-Alcalde D, Rosenbaum T. Structural determinants of the transient receptor potential 1 (TRPV1) channel activation by phospholipid analogs J Biol Chem. 2014 Aug 29;289(35):24079-90.
3: Liliom K, Murakami-Murofushi K, Kobayashi S, Murofushi H, Tigyi G. Xenopus oocytes express multiple receptors for LPA-like lipid mediators Am J Physiol. 1996 Mar;270(3 Pt 1):C772-7.
4: Altman MK, Gopal V, Jia W, Yu S, Hall H, Mills GB, McGinnis AC, Bartlett MG, Jiang G, Madan D, Prestwich GD, Xu Y, Davies MA, Murph MM. Targeting melanoma growth and viability reveals dualistic functionality of the phosphonothionate analogue of carba cyclic phosphatidic acid Mol Cancer. 2010 Jun 9;9:140.
5: Lee S, Lynch KR. Brown recluse spider (Loxosceles reclusa) venom phospholipase D (PLD) generates lysophosphatidic acid (LPA) Biochem J. 2005 Oct 15;391(Pt 2):317-23.
6: Antonia SJ, Villegas A, Daniel D, Vicente D, Murakami S, Hui R, Yokoi T, Chiappori A, Lee KH, de Wit M, Cho BC, Bourhaba M, Quantin X, Tokito T, Mekhail T, Planchard D, Kim YC, Karapetis CS, Hiret S, Ostoros G, Kubota K, Gray JE, Paz-Ares L, de Castro Carpeño J, Wadsworth C, Melillo G, Jiang H, Huang Y, Dennis PA, Özgüroğlu M; PACIFIC Investigators. Durvalumab after Chemoradiotherapy in Stage III Non-Small-Cell Lung Cancer N Engl J Med. 2017 Nov 16;377(20):1919-1929.
7: Kelly JF, Humphreys K, Ferri M. Alcoholics Anonymous and other 12-step programs for alcohol use disorder Cochrane Database Syst Rev. 2020 Mar 11;3(3):CD012880.
8: Cerutis DR, Weston MD, Ogunleye AO, McVaney TP, Miyamoto T. Lysophosphatidic acid (LPA) 18:1 transcriptional regulation of primary human gingival fibroblasts Genom Data. 2014 Oct 23;2:375-7.
9: Cao J, Martin-Lorenzo M, van Kuijk K, Wieland EB, Gijbels MJ, Claes BSR, Heredero A, Aldamiz-Echevarria G, Heeren RMA, Goossens P, Sluimer JC, Balluff B, Alvarez-Llamas G. Spatial Metabolomics Identifies LPC(18:0) and LPA(18:1) in Advanced Atheroma With Translation to Plasma for Cardiovascular Risk Estimation Arterioscler Thromb Vasc Biol. 2024 Mar;44(3):741-754.
10: Ma L, Nagai J, Chun J, Ueda H. An LPA species (18:1 LPA) plays key roles in the self-amplification of spinal LPA production in the peripheral neuropathic pain model Mol Pain. 2013 Jun 17;9:29.

Products Related to 1-oleoyl-sn-glycero-2,3-cyclic-phosphate, 18:1 Cyclic LPA can be found at Lipids

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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