1-oleoyl-2-hydroxy-sn-glycero-3-phosphate, 18:1 Lyso PA
Original price was: $1,595.00.$795.00Current price is: $795.00.
Catalog Number: B2019000 (5 mg)
1-oleoyl-2-hydroxy-sn-glycero-3-phosphate, or 18:1 Lyso PA, is a lysophospholipid derived from phosphatidic acid. It features a glycerol backbone with an oleoyl group and a phosphate group, making it significant in cell signaling pathways that regulate growth and migration. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
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In stock
Product Description
1-oleoyl-2-hydroxy-sn-glycero-3-phosphate, 18:1 Lyso PA
Catalog number: B2019000
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 458 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: 18:1 Lyso PA, 1-oleoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), oleoyl lysophosphatidic acid, 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate (sodium salt), PA(18:1(9Z)/0:0), 18:1 LPAo-LPA, 110681
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Otoki Y, Yu D, Shen Q, Sahlas DJ, Ramirez J, Gao F, Masellis M, Swartz RH, Chan PC, Pettersen JA, Kato S, Nakagawa K, Black SE, Swardfager W, Taha AY. Quantitative Lipidomic Analysis of Serum Phospholipids Reveals Dissociable Markers of Alzheimer’s Disease and Subcortical Cerebrovascular Disease J Alzheimers Dis. 2023;93(2):665-682.
2: Gajewiak J, Tsukahara R, Tsukahara T, Fujiwara Y, Yu S, Lu Y, Murph M, Mills GB, Tigyi G, Prestwich GD. Alkoxymethylenephosphonate analogues of (Lyso) phosphatidic acid stimulate signaling networks coupled to the LPA2 receptor ChemMedChem. 2007 Dec;2(12):1789-98.
3: Mishra S, Kell P, Scherrer D, Dietzen DJ, Vite CH, Berry-Kravis E, Davidson C, Cologna SM, Porter FD, Ory DS, Jiang X. Accumulation of alkyl-lysophosphatidylcholines in Niemann-Pick disease type C1 J Lipid Res. 2024 Aug;65(8):100600.
4: Yang L, Wang L, Deng Y, Sun L, Lou B, Yuan Z, Wu Y, Zhou B, Liu J, She J. Serum lipids profiling perturbances in patients with ischemic heart disease and ischemic cardiomyopathy Lipids Health Dis. 2020 May 9;19(1):89.
5: Cadenas C, Vosbeck S, Hein EM, Hellwig B, Langer A, Hayen H, Franckenstein D, Büttner B, Hammad S, Marchan R, Hermes M, Selinski S, Rahnenführer J, Peksel B, Török Z, VÃgh L, Hengstler JG. Glycerophospholipid profile in oncogene-induced senescence Biochim Biophys Acta. 2012 Sep;1821(9):1256-68.
6: Rajakumari S, Srivastava S. Aging and β3-adrenergic stimulation alter mitochondrial lipidome of adipose tissue Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Jul;1866(7):158922.
7: Calvano CD, Bianco M, Ventura G, Losito I, Palmisano F, Cataldi TRI. Analysis of Phospholipids, Lysophospholipids, and Their Linked Fatty Acyl Chains in Yellow Lupin Seeds (Lupinus luteus L.) by Liquid Chromatography and Tandem Mass Spectrometry Molecules. 2020 Feb 13;25(4):805.
8: Kimura T, Kimura AK, Ren M, Berno B, Xu Y, Schlame M, Epand RM. Substantial Decrease in Plasmalogen in the Heart Associated with Tafazzin Deficiency Biochemistry. 2018 Apr 10;57(14):2162-2175.
9: Granger MW, Liu H, Fowler CF, Blanchard AP, Taylor MW, Sherman SPM, Xu H, Le W, Bennett SAL. Distinct disruptions in Land’s cycle remodeling of glycerophosphocholines in murine cortex mark symptomatic onset and progression in two Alzheimer’s disease mouse models J Neurochem. 2019 May;149(4):499-517.
10: Frasch SC, Berry KZ, Fernandez-Boyanapalli R, Jin HS, Leslie C, Henson PM, Murphy RC, Bratton DL. NADPH oxidase-dependent generation of lysophosphatidylserine enhances clearance of activated and dying neutrophils via G2A J Biol Chem. 2008 Nov 28;283(48):33736-49.
Products Related to 1-oleoyl-2-hydroxy-sn-glycero-3-phosphate, 18:1 Lyso PA can be found at Lipids
Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |
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