α-Ketoglutaric Acid (Highly Pure)

Product Description

α-Ketoglutaric Acid (Highly Pure)
Catalog number: B2012617
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 g
Molecular Weight or Concentration: 146.1 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: α-KGA, NSC 17391, 2-Oxoglutaric Acid
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Niu P, Dong X, Wang Y, Liu L. Enzymatic production of α-ketoglutaric acid from l-glutamic acid via l-glutamate oxidase J Biotechnol. 2014 Jun 10;179:56-62.
2: Chen X, Dong X, Liu J, Luo Q, Liu L. Pathway engineering of Escherichia coli for α-ketoglutaric acid production Biotechnol Bioeng. 2020 Sep;117(9):2791-2801.
3: Kamzolova SV, Morgunov IG. Optimization of medium composition and fermentation conditions for α-ketoglutaric acid production from biodiesel waste by Yarrowia lipolytica Appl Microbiol Biotechnol. 2020 Sep;104(18):7979-7989.
4: Luo Z, Yu S, Zeng W, Zhou J. Comparative analysis of the chemical and biochemical synthesis of keto acids Biotechnol Adv. 2021 Mar-Apr;47:107706.
5: Moore SJ, Norris JC, Ho IK, Hume AS. The efficacy of alpha-ketoglutaric acid in the antagonism of cyanide intoxication Toxicol Appl Pharmacol. 1986 Jan;82(1):40-4.
6: Kamzolova SV, Chiglintseva MN, Lunina JN, Morgunov IG. α-Ketoglutaric acid production by Yarrowia lipolytica and its regulation Appl Microbiol Biotechnol. 2012 Nov;96(3):783-91.
7: Peng X, Zeng W, Xu S, Zha J, Zhou J, Xu G. Separation of α_ketoglutaric acid and pyruvic acid from the culture broth of Yarrowia lipolytica WSH-Z06 by chromatographic methods Biotechnol Prog. 2018 Nov;34(6):1370-1379.
8: Kamzolova SV, Morgunov IG. α-Ketoglutaric acid production from rapeseed oil by Yarrowia lipolytica yeast Appl Microbiol Biotechnol. 2013 Jun;97(12):5517-25.
9: Shen D, Kruger L, Deatherage T, Denton TT. Synthesis of α-Ketoglutaramic acid Anal Biochem. 2020 Oct 15;607:113862.
10: Masip J, Rallón N, Yeregui E, Olona M, Resino S, Benito JM, Viladés C, García-Pardo G, Alcamí J, Ruiz-Mateos E, Gómez-Bertomeu F, Vargas M, Navarro M, Oteo JA, Pineda JA, Martí A, Alba V, Vidal F, Peraire J, Rull A. Elevated α-Ketoglutaric Acid Concentrations and a Lipid-Balanced Signature Are the Key Factors in Long-Term HIV Control Front Immunol. 2022 Apr 20;13:822272.

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