Sulforhodamine 101 (Highly Pure)


Catalog Number: B2012413 (50 mg)
Sulforhodamine 101 (Highly Pure) is a high quality nonfixable red fluorescent dye. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Sulforhodamine 101 (Highly Pure)
Catalog number: B2012413
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 mg
Molecular Weight or Concentration: 606.7 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: SR 101, Sulforhodamine 640
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Hülsmann S, Hagos L, Heuer H, Schnell C. Limitations of Sulforhodamine 101 for Brain Imaging Front Cell Neurosci. 2017 Feb 28;11:44.
2: Akanuma SI, Kida R, Tsuchiyama A, Tachikawa M, Kubo Y, Hosoya KI. Organic anion-transporting polypeptide 1a4-mediated heterogeneous distribution of sulforhodamine-101 in rat hepatic lobules Drug Metab Pharmacokinet. 2019 Aug;34(4):239-246.
3: Schnell C, Hagos Y, Hülsmann S. Active sulforhodamine 101 uptake into hippocampal astrocytes PLoS One. 2012;7(11):e49398.
4: Georges JF, Martirosyan NL, Eschbacher J, Nichols J, Tissot M, Preul MC, Feuerstein B, Anderson T, Spetzler RF, Nakaji P. Sulforhodamine 101 selectively labels human astrocytoma cells in an animal model of glioblastoma J Clin Neurosci. 2014 May;21(5):846-51.
5: Rasmussen R, Nedergaard M, Petersen NC. Sulforhodamine_101, a widely used astrocyte marker, can induce cortical seizure-like activity at concentrations commonly used Sci Rep. 2016 Jul 26;6:30433.
6: Yaguchi Y, Tachikawa M, Zhang Z, Terasaki T. Organic Anion-Transporting Polypeptide 1a4 (Oatp1a4/Slco1a4) at the Blood-Arachnoid Barrier is the Major Pathway of Sulforhodamine_101 Clearance from Cerebrospinal Fluid of Rats Mol Pharm. 2019 May 6;16(5):2021-2027.
7: Nimmerjahn A, Kirchhoff F, Kerr JN, Helmchen F. Sulforhodamine_101 as a specific marker of astroglia in the neocortex in vivo Nat Methods. 2004 Oct;1(1):31-7.
8: Hill RA, Grutzendler J. In vivo imaging of oligodendrocytes with sulforhodamine_101 Nat Methods. 2014 Nov;11(11):1081-2.
9: Kang J, Kang N, Yu Y, Zhang J, Petersen N, Tian GF, Nedergaard M. Sulforhodamine_101 induces long-term potentiation of intrinsic excitability and synaptic efficacy in hippocampal CA1 pyramidal neurons Neuroscience. 2010 Sep 15;169(4):1601-9.
10: Kreimerman I, Reyes AL, Paolino A, Pardo T, Porcal W, Ibarra M, Oliver P, Savio E, Engler H. Biological Assessment of a (18)F-Labeled Sulforhodamine 101 in a Mouse Model of Alzheimer’s Disease as a Potential Astrocytosis Marker Front Neurosci. 2019 Jul 16;13:734.

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