Polysorbate 80 (Highly Pure)

Product Description

Polysorbate 80 (Highly Pure)
Catalog number: B2017700
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 g
Molecular Weight or Concentration: 79000
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: RT
Keywords: Polysorbatum 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Schwartzberg LS, Navari RM. Safety of Polysorbate 80 in the Oncology Setting Adv Ther. 2018 Jun;35(6):754-767.
2: Tang C, Zhao Y, Liu J, Zheng X, Guo X, Liu H, Chen L, Shi Y. Polysorbate 80 as a possible allergenic component in cross-allergy to docetaxel and fosaprepitant: A literature review J Oncol Pharm Pract. 2023 Dec;29(8):1998-2006.
3: Kim RE, Choi JS. Polysorbate 80 blocked a peripheral sodium channel, Na(v)1.7, and reduced neuronal excitability Mol Pain. 2023 Jan-Dec;19:17448069221150138.
4: Kerwin BA. Polysorbates 20 and 80 used in the formulation of protein biotherapeutics: structure and degradation pathways J Pharm Sci. 2008 Aug;97(8):2924-35.
5: Gilbert PH, Zhang Z, Qian KK, Allen DP, Wagner NJ, Liu Y. Preservative Induced Polysorbate 80 Micelle Aggregation J Pharm Sci. 2021 Jun;110(6):2395-2404.
6: Yano S, Terada S, Fukushi M, Otsuka Y, Mizunuma S, Asakura S, Kawai T, Konno H, Endo M, Nonomura Y. Antimicrobial Activity of Polysorbate 80-iodine Complex: Polysorbate 80 Firmly Retains Iodine J Oleo Sci. 2022 Oct 28;71(11):1639-1645.
7: Zheng X, Sutton AT, Yang RS, Miller DV, Pagels B, Rustandi RR, Welch J, Payne A, Haverick M. Extensive Characterization of Polysorbate 80 Oxidative Degradation Under Stainless Steel Conditions J Pharm Sci. 2023 Mar;112(3):779-789.
8: Zhou X, Fennema Galparsoro D, Østergaard Madsen A, Vetri V, van de Weert M, Mørck Nielsen H, Foderà V. Polysorbate 80 controls Morphology, structure and stability of human insulin Amyloid-Like spherulites J Colloid Interface Sci. 2022 Jan 15;606(Pt 2):1928-1939.
9: Ogulur I, Yazici D, Pat Y, Bingöl EN, Babayev H, Ardicli S, Heider A, Rückert B, Sampath V, Dhir R, Akdis M, Nadeau K, Akdis CA. Mechanisms of gut epithelial barrier impairment caused by food emulsifiers polysorbate 20 and polysorbate 80 Allergy. 2023 Sep;78(9):2441-2455.
10: Schmidt A, Koulov A, Huwyler J, Mahler HC, Jahn M. Stabilizing Polysorbate 20 and 80 Against Oxidative Degradation J Pharm Sci. 2020 Jun;109(6):1924-1932.

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