Polyporus squamosus Lectin Conjugated to Agarose


Catalog Number: B2011037 (2 mL suspension)
Polyporus squamosus Lectin Conjugated to Agarose is a high quality PSL1a coupled to an agarose gel. This product has been used as molecular tool for various chemical, biochemical and immunological applications. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Polyporus squamosus Lectin Conjugated to Agarose
Catalog number: B2011037
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 2 mL suspension
Molecular Weight or Concentration: na
Supplied as: Suspension
Applications: molecular tool for various chemical, biochemical and immunological applications
Storage: 2-8°C (do not freeze)
Keywords: rPSL1a-Agarose, PSL1a-Agarose
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Manna D, Pust S, Torgersen ML, Cordara G, Künzler M, Krengel U, Sandvig K. Polyporus squamosus Lectin 1a (PSL1a) Exhibits Cytotoxicity in Mammalian Cells by Disruption of Focal Adhesions, Inhibition of Protein Synthesis and Induction of Apoptosis PLoS One. 2017 Jan 23;12(1):e0170716.
2: Arigi E, Singh S, Kahlili AH, Winter HC, Goldstein IJ, Levery SB. Characterization of neutral and acidic glycosphingolipids from the lectin-producing mushroom, Polyporus squamosus Glycobiology. 2007 Jul;17(7):754-66.
3: Mo H, Winter HC, Goldstein IJ. Purification and characterization of a Neu5Acalpha2-6Galbeta1-4Glc/GlcNAc-specific lectin from the fruiting body of the polypore mushroom Polyporus squamosus J Biol Chem. 2000 Apr 7;275(14):10623-9.
4: Kadirvelraj R, Grant OC, Goldstein IJ, Winter HC, Tateno H, Fadda E, Woods RJ. Structure and binding analysis of Polyporus squamosus lectin in complex with the Neu5Ac{alpha}2-6Gal{beta}1-4GlcNAc human-type influenza receptor Glycobiology. 2011 Jul;21(7):973-84.
5: Tateno H, Winter HC, Goldstein IJ. Cloning, expression in Escherichia coli and characterization of the recombinant Neu5Acalpha2,6Galbeta1,4GlcNAc-specific high-affinity lectin and its mutants from the mushroom Polyporus squamosus Biochem J. 2004 Sep 1;382(Pt 2):667-75.
6: Zhang B, Palcic MM, Mo H, Goldstein IJ, Hindsgaul O. Rapid determination of the binding affinity and specificity of the mushroom Polyporus squamosus lectin using frontal affinity chromatography coupled to electrospray mass spectrometry Glycobiology. 2001 Feb;11(2):141-7.
7: Kobayashi Y, Kawagishi H. Fungal lectins: a growing family Methods Mol Biol. 2014;1200:15-38.
8: Cordara G, Manna D, Krengel U. Family of Papain-Like Fungal Chimerolectins with Distinct Ca(2+)-Dependent Activation Mechanism Biochemistry. 2017 Sep 5;56(35):4689-4700.
9: Malagolini N, Chiricolo M, Marini M, Dall’Olio F. Exposure of alpha2,6-sialylated lactosaminic chains marks apoptotic and necrotic death in different cell types Glycobiology. 2009 Feb;19(2):172-81.
10: Zuber C, Paulson JC, Toma V, Winter HC, Goldstein IJ, Roth J. Spatiotemporal expression patterns of sialoglycoconjugates during nephron morphogenesis and their regional and cell type-specific distribution in adult rat kidney Histochem Cell Biol. 2003 Aug;120(2):143-60.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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