N-Glycine Galactosylsphingosine (d18:1)

Product Description

N-Glycine Galactosylsphingosine (d18:1)
Catalog number: B2017545
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 518.7
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: N-Glycinated Galactosylsphingosine, N-Glycine Psychosine
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: LaMarco KL, Glew RH. Galactosylsphingosine inhibition of the broad-specificity cytosolic beta-glucosidase of human liver Arch Biochem Biophys. 1985 Feb 1;236(2):669-76.
2: Goldstein AS, Lukyanov AN, Carlson PA, Yager P, Gelb MH. Formation of high-axial-ratio-microstructures from natural and synthetic sphingolipids Chem Phys Lipids. 1997 Aug 8;88(1):21-36.
3: Anttinen H, Myllylä R, Kivirikko KI. Further characterization of galactosylhydroxylysyl glucosyltransferase from chick embryos. Amino acid composition and acceptor specificity Biochem J. 1978 Nov 1;175(2):737-42.
4: Rosengren B, Fredman P, Månsson JE, Svennerholm L. Lysosulfatide (galactosylsphingosine-3-O-sulfate) from metachromatic leukodystrophy and normal human brain J Neurochem. 1989 Apr;52(4):1035-41.
5: Cabasso O, Kuppuramalingam A, Lelieveld L, Van der Lienden M, Boot R, Aerts JM, Horowitz M. Animal Models for the Study of Gaucher Disease Int J Mol Sci. 2023 Nov 7;24(22):16035.
6: Qu J, Zong HF, Shan Y, Zhang SC, Guan WP, Yang Y, Zhao HL. Piezo1 suppression reduces demyelination after intracerebral hemorrhage Neural Regen Res. 2023 Aug;18(8):1750-1756.
7: Svennerholm L, Vanier MT, Månsson JE. Krabbe disease: a galactosylsphingosine (psychosine) lipidosis J Lipid Res. 1980 Jan;21(1):53-64.
8: Goda S, Kobayashi T, Goto I. Hydrolysis of galactosylsphingosine and lactosylsphingosine by beta-galactosidases in human brain and cultured fibroblasts Biochim Biophys Acta. 1987 Aug 15;920(3):259-65.
9: Misslin C, Velasco-Estevez M, Albert M, O’Sullivan SA, Dev KK. Phospholipase A2 is involved in galactosylsphingosine-induced astrocyte toxicity, neuronal damage and demyelination PLoS One. 2017 Nov 2;12(11):e0187217.
10: Giri S, Jatana M, Rattan R, Won JS, Singh I, Singh AK. Galactosylsphingosine (psychosine)-induced expression of cytokine-mediated inducible nitric oxide synthases via AP-1 and C/EBP: implications for Krabbe disease FASEB J. 2002 May;16(7):661-72.

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