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Methylmalonyl Coenzyme A Tetralithium Salt Hydrate

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2015998 (250 ug)
Methylmalonyl Coenzyme A Tetralithium Salt Hydrate is a high quality Coenzyme A that functions as an acyl group carrier. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

Methylmalonyl Coenzyme A Tetralithium Salt Hydrate
Catalog number: B2015998
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 250 ug
Molecular Weight or Concentration: 891.34 (anhydrous basis)
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20 °C
Keywords: α-Methylmalonyl coenzyme A tetralithium salt, MM-CoA
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Forny P, Bonilla X, Lamparter D, Shao W, Plessl T, Frei C, Bingisser A, Goetze S, van Drogen A, Harshman K, Pedrioli PGA, Howald C, Poms M, Traversi F, Bürer C, Cherkaoui S, Morscher RJ, Simmons L, Forny M, Xenarios I, Aebersold R, Zamboni N, Rätsch G, Dermitzakis ET, Wollscheid B, Baumgartner MR, Froese DS. Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency Nat Metab. 2023 Jan;5(1):80-95.
2: Gomes AP, Ilter D, Low V, Drapela S, Schild T, Mullarky E, Han J, Elia I, Broekaert D, Rosenzweig A, Nagiec M, Nunes JB, Schaffer BE, Mutvei AP, Asara JM, Cantley LC, Fendt SM, Blenis J. Altered propionate metabolism contributes to tumour progression and aggressiveness Nat Metab. 2022 Apr;4(4):435-443.
3: Manoli I, Sloan JL, Venditti CP. Isolated Methylmalonic Acidemia 2005 Aug 16 [updated 2022 Sep 8]. In: Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, editors. GeneReviews(®) [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2024.
4: Diogo R, Rua IB, Ferreira S, Nogueira C, Pereira C, Rosmaninho-Salgado J, Diogo L. Methylmalonyl Coenzyme A (CoA) Epimerase Deficiency, an Ultra-Rare Cause of Isolated Methylmalonic Aciduria With Predominant Neurological Features Cureus. 2023 Oct 31;15(10):e48017.
5: Sokolovskaya OM, Mok KC, Park JD, Tran JLA, Quanstrom KA, Taga ME. Cofactor Selectivity in Methylmalonyl Coenzyme A Mutase, a Model Cobamide-Dependent Enzyme mBio. 2019 Sep 24;10(5):e01303-19.
6: El Hadadi F, Mezni L, Ismaili N, Benzekri L, Senouci K. Acrodermatitis enteropathica-like eruption JAAD Case Rep. 2022 Mar 25;24:20-23.
7: Padmakumar R, Gantla S, Banerjee R. A rapid method for the synthesis of methylmalonyl-coenzyme A and other CoA-esters Anal Biochem. 1993 Oct;214(1):318-20.
8: Hunaiti AA, Kolattukudy PE. Source of methylmalonyl-coenzyme A for erythromycin synthesis: methylmalonyl-coenzyme A mutase from Streptomyces erythreus Antimicrob Agents Chemother. 1984 Feb;25(2):173-8.
9: Gotoh K, Nakajima Y, Tajima G, Watanabe Y, Hotta Y, Kataoka T, Kawade Y, Sugiyama N, Ito T, Kimura K, Maeda Y. Determination of methylmalonyl coenzyme A by ultra high-performance liquid chromatography tandem mass spectrometry for measuring propionyl coenzyme A carboxylase activity in patients with propionic acidemia J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Mar 1;1046:195-199.
10: Methylmalonyl coenzyme A and fatty acid synthesis by rat liver enzymes in vitro Nutr Rev. 1970 Nov;28(11):301-3.

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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