Kininogen Single Chain HMW from Plasma

Product Description

Kininogen Single Chain HMW from Plasma
Catalog number: B2016893
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 120 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -80°C
Keywords: Kininogen-1, High molecular weight kininogen (HMWK)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Mori K, Nagasawa S. Studies on human high molecular weight (HMW) kininogen. II. Structural change of HMW kininogen by the action of human plasma kallikrein J Biochem. 1981 May;89(5):1465-73.
2: Mori K, Sakamoto W, Nagasawa S. Studies on human high molecular weight (HMW) kininogen. III. Cleavage of HMW kininogen by the action of human salivary kallikrein J Biochem. 1981 Aug;90(2):503-9.
3: Nakayasu T, Nagasawa S. Studies on human kininogens. I. Isolation, characterization, and cleavage by plasma kallikrein of high molecular weight (HMW)-kininogen J Biochem. 1979 Jan;85(1):249-58.
4: Müller-Esterl W, Hock H, Rauth G, Kellermann J, Lottspeich F, Henschen A. Limited proteolysis of HMW kininogen by plasma kallikrein in man–evidence for a processing mechanism different from the bovine system Adv Exp Med Biol. 1986;198 Pt A:97-103.
5: Higashiyama S, Ohkubo I, Ishiguro H, Kunimatsu M, Sawaki K, Sasaki M. Human high molecular weight kininogen as a thiol proteinase inhibitor: presence of the entire inhibition capacity in the native form of heavy chain Biochemistry. 1986 Apr 8;25(7):1669-75.
6: Thompson RE, Mandle R Jr, Kaplan AP. Characterization of human high molecular weight kininogen. Procoagulant activity associated with the light chain of kinin-free high molecular weight kininogen J Exp Med. 1978 Feb 1;147(2):488-99.
7: Kleniewski J, Donaldson VH. Comparison of human high molecular weight kininogen digestion by plasma kallikrein and by plasmin. A revised method of purification of high molecular weight kininogen J Lab Clin Med. 1987 Apr;109(4):469-79.
8: Lämmle B, Zuraw BL, Heeb MJ, Schwarz HP, Berrettini M, Curd JG, Griffin JH. Detection and quantitation of cleaved and uncleaved high molecular weight kininogen in plasma by ligand blotting with radiolabeled plasma prekallikrein or factor XI Thromb Haemost. 1988 Apr 8;59(2):151-61.
9: Muller-Esterl W, Dittmann B, Fritz H, Lottspeich F, Henschen A. Structural aspects of human kininogens Adv Exp Med Biol. 1983;156:157-64.
10: Semba U, Umeda Y, Shibuya Y, Okabe H, Tanase S, Yamamoto T. Primary structures of guinea pig high- and low-molecular-weight kininogens Int Immunopharmacol. 2004 Oct;4(10-11):1391-400.

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