Human Complement Factor D Deficient Serum

Product Description

Human Complement Factor D Deficient Serum
Catalog number: B2015460
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mL
Molecular Weight or Concentration: N/A
Supplied as: Serum
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Adipsin, Adipsin/Complement Factor D, And, C3 Convertase Activator, CFAD, CFD, D Component of Complement, DF, FactorD, PFD, Properdin Factor D
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Langereis JD, van der Molen RG, de Kat Angelino C, Henriet SS, de Jonge MI, Joosten I, Simons A, Schuurs-Hoeijmakers JH, van Deuren M, van Aerde K, van der Flier M. Complement factor D haplodeficiency is associated with a reduced complement activation speed and diminished bacterial killing Clin Transl Immunology. 2021 Apr 3;10(4):e1256.
2: Sjöholm AG, Selander B, Ostenson S, Holmström E, Söderström C. Normal human serum depleted of C1q, factor D and properdin: its use in studies of complement activation APMIS. 1991 Dec;99(12):1120-8.
3: Dare A, Chen SY. Adipsin in the pathogenesis of cardiovascular diseases Vascul Pharmacol. 2023 Dec 17;154:107270.
4: Wu X, Hutson I, Akk AM, Mascharak S, Pham CTN, Hourcade DE, Brown R, Atkinson JP, Harris CA. Contribution of Adipose-Derived Factor D/Adipsin to Complement Alternative Pathway Activation: Lessons from Lipodystrophy J Immunol. 2018 Apr 15;200(8):2786-2797.
5: Menger M, Aston WP. Factor D of the alternative pathway of bovine complement: isolation and characterization Vet Immunol Immunopathol. 1984 Oct;7(3-4):325-36.
6: Dani R, Oroszlán G, Martinusz R, Farkas B, Dobos B, Vadas E, Závodszky P, Gál P, Dobó J. Quantification of the zymogenicity and the substrate-induced activity enhancement of complement factor D Front Immunol. 2023 May 22;14:1197023.
7: Biesma DH, Hannema AJ, van Velzen-Blad H, Mulder L, van Zwieten R, Kluijt I, Roos D. A family with complement factor D deficiency J Clin Invest. 2001 Jul;108(2):233-40.
8: Cohen G, Haag-Weber M, Hörl WH. Immune dysfunction in uremia Kidney Int Suppl. 1997 Nov;62:S79-82.
9: Hiemstra PS, Langeler E, Compier B, Keepers Y, Leijh PC, van den Barselaar MT, Overbosch D, Daha MR. Complete and partial deficiencies of complement factor D in a Dutch family J Clin Invest. 1989 Dec;84(6):1957-61.
10: Ballow M, Kennedy TL 3rd, Gaudio KM, Siegel NJ, McLean RH. Serum hemolytic factor D values in children with steroid-responsive idiopathic nephrotic syndrome J Pediatr. 1982 Feb;100(2):192-6.

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