Human CLC Protein


Catalog Number: B2011967 (100 µg)
Human CLC Protein is a high quality recombinant human CLC protein His tagged and expressed in E.coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human CLC Protein
Catalog number: B2011967
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 0.5 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Galectin 10 protein, LGALS10 protein, Gal-10 protein, LPPL protein, Eosinophil lysophospholipase protein, LGALS10A protein, GAL10 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Jentsch TJ, Pusch M. CLC Chloride Channels and Transporters: Structure, Function, Physiology, and Disease Physiol Rev. 2018 Jul 1;98(3):1493-1590.
2: Lagostena L, Zifarelli G, Picollo A. New Insights into the Mechanism of NO(3) (-) Selectivity in the Human Kidney Chloride Channel ClC-Ka and the CLC Protein Family J Am Soc Nephrol. 2019 Feb;30(2):293-302.
3: Wang K, Preisler SS, Zhang L, Cui Y, Missel JW, Grønberg C, Gotfryd K, Lindahl E, Andersson M, Calloe K, Egea PF, Klaerke DA, Pusch M, Pedersen PA, Zhou ZH, Gourdon P. Structure of the human ClC-1 chloride channel PLoS Biol. 2019 Apr 25;17(4):e3000218.
4: Zhang S, Liu Y, Zhang B, Zhou J, Li T, Liu Z, Li Y, Yang M. Molecular insights into the human CLC-7/Ostm1 transporter Sci Adv. 2020 Aug 12;6(33):eabb4747.
5: Riisager A, de Paoli FV, Yu WP, Pedersen TH, Chen TY, Nielsen OB. Protein kinase C-dependent regulation of ClC-1 channels in active human muscle and its effect on fast and slow gating J Physiol. 2016 Jun 15;594(12):3391-406.
6: Peng YJ, Lee YC, Fu SJ, Chien YC, Liao YF, Chen TY, Jeng CJ, Tang CY. FKBP8 Enhances Protein Stability of the CLC-1 Chloride Channel at the Plasma Membrane Int J Mol Sci. 2018 Nov 28;19(12):3783.
7: Gu Z, Wang L, Yao X, Long Q, Lee K, Li J, Yue D, Yang S, Liu Y, Li N, Li Y. ClC-3/SGK1 regulatory axis enhances the olaparib-induced antitumor effect in human stomach adenocarcinoma Cell Death Dis. 2020 Oct 22;11(10):898.
8: Thomassen M, Hostrup M, Murphy RM, Cromer BA, Skovgaard C, Gunnarsson TP, Christensen PM, Bangsbo J. Abundance of ClC-1 chloride channel in human skeletal muscle: fiber type specific differences and effect of training J Appl Physiol (1985). 2018 Aug 1;125(2):470-478.
9: Melo RCN, Wang H, Silva TP, Imoto Y, Fujieda S, Fukuchi M, Miyabe Y, Hirokawa M, Ueki S, Weller PF. Galectin-10, the protein that forms Charcot-Leyden crystals, is not stored in granules but resides in the peripheral cytoplasm of human eosinophils J Leukoc Biol. 2020 Jul;108(1):139-149.
10: Hezavehei M, Sharafi M, Fathi R, Shahverdi A, Gilani MAS. Membrane lipid replacement with nano-micelles in human sperm cryopreservation improves post-thaw function and acrosome protein integrity Reprod Biomed Online. 2021 Aug;43(2):257-268.

Products Related to Human CLC Protein can be found at Proteins

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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