Heart Myosin Light Chain (MLC) Kinase (Native Human)

Product Description

Heart Myosin Light Chain (MLC) Kinase (Native Human)
Catalog number: B2016904
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 μg
Molecular Weight or Concentration: N/A
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: Native Human Heart Myosin Light Chain (MLC) Kinase
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Morano I, Hädicke K, Grom S, Koch A, Schwinger RH, Böhm M, Bartel S, Erdmann E, Krause EG. Titin, myosin light chains and C-protein in the developing and failing human heart J Mol Cell Cardiol. 1994 Mar;26(3):361-8.
2: Wraith KS, Magwenzi S, Aburima A, Wen Y, Leake D, Naseem KM. Oxidized low-density lipoproteins induce rapid platelet activation and shape change through tyrosine kinase and Rho kinase-signaling pathways Blood. 2013 Jul 25;122(4):580-9.
3: Sheikh F, Lyon RC, Chen J. Functions of myosin light chain-2 (MYL2) in cardiac muscle and disease Gene. 2015 Sep 10;569(1):14-20.
4: Srivastava N, Tauseef M, Amin R, Joshi B, Joshi JC, Kini V, Klomp J, Li W, Knezevic N, Barbera N, Siddiqui S, Obukhov A, Karginov A, Levitan I, Komarova Y, Mehta D. Noncanonical function of long myosin light chain kinase in increasing ER-PM junctions and augmentation of SOCE FASEB J. 2020 Sep;34(9):12805-12819.
5: Grimm M, Haas P, Willipinski-Stapelfeldt B, Zimmermann WH, Rau T, Pantel K, Weyand M, Eschenhagen T. Key role of myosin light chain (MLC) kinase-mediated MLC2a phosphorylation in the alpha 1-adrenergic positive inotropic effect in human atrium Cardiovasc Res. 2005 Jan 1;65(1):211-20.
6: Morano I, Hädicke K, Grom S, Koch A, Schwinger RH, Böhm M, Bartel S, Erdmann E, Krause EG. Titin, myosin light chains and C-protein in the developing and failing human heart J Mol Cell Cardiol. 1994 Mar;26(3):361-8.
7: Shichi D, Arimura T, Ishikawa T, Kimura A. Heart-specific small subunit of myosin light chain phosphatase activates rho-associated kinase and regulates phosphorylation of myosin phosphatase target subunit 1 J Biol Chem. 2010 Oct 29;285(44):33680-90.
8: Aburima A, Wraith KS, Raslan Z, Law R, Magwenzi S, Naseem KM. cAMP signaling regulates platelet myosin light chain (MLC) phosphorylation and shape change through targeting the RhoA-Rho kinase-MLC phosphatase signaling pathway Blood. 2013 Nov 14;122(20):3533-45.
9: Kockskämper J, Khafaga M, Grimm M, Elgner A, Walther S, Kockskämper A, von Lewinski D, Post H, Grossmann M, Dörge H, Gottlieb PA, Sachs F, Eschenhagen T, Schöndube FA, Pieske B. Angiotensin II and myosin light-chain phosphorylation contribute to the stretch-induced slow force response in human atrial myocardium Cardiovasc Res. 2008 Sep 1;79(4):642-51.
10: Hwang J, Pallas DC. STRIPAK complexes: structure, biological function, and involvement in human diseases Int J Biochem Cell Biol. 2014 Feb;47:118-48.

Products Related to Heart Myosin Light Chain (MLC) Kinase (Native Human) can be found at Biofluids