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Glycodehydrocholic Acid (Highly Pure)

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2017539 (5 mg)
Glycodehydrocholic acid is a bile acid that plays a role in the digestion and absorption of fats in the small intestine by helping emulsify fats for easier breakdown by enzymes into absorbable molecules. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

Glycodehydrocholic Acid (Highly Pure)
Catalog number: B2017539
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 459.6
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Glycine Dehydrocholate
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Parkhill BJ Jr, Barnhart JL, Combes B. Hepatic metabolism of glycodehydrocholic acid in the dog and rat Proc Soc Exp Biol Med. 1979 Dec;162(3):495-502.
2: Montet JC, Gerolami A, Durbec JP, Crotte C, Montet AM, Hauton JC. Hepatic uptake and biliary excretion of a bile salt analog : glycodihydrofusidate Biomedicine. 1977 Feb;26(1):60-4.
3: Guzior DV, Quinn RA. Review: microbial transformations of human bile acids Microbiome. 2021 Jun 14;9(1):140.
4: Chen T, Zhou K, Sun T, Sang C, Jia W, Xie G. Altered bile acid glycine : taurine ratio in the progression of chronic liver disease J Gastroenterol Hepatol. 2022 Jan;37(1):208-215.
5: Hasan MN, Chen J, Wang H, Du Y, Clayton YD, Gu L, Li T. Glycine-β-Muricholic Acid Improves Liver Fibrosis and Gut Barrier Function by Reducing Bile Acid Pool Size and Hydrophobicity in Male Cyp2c70 Knockout Mice Cells. 2023 May 12;12(10):1371.
6: Heubi JE, Setchell KD, Jha P, Buckley D, Zhang W, Rosenthal P, Potter C, Horslen S, Suskind D. Treatment of bile acid amidation defects with glycocholic acid Hepatology. 2015 Jan;61(1):268-74.
7: Fitzinger J, Rodriguez-Blanco G, Herrmann M, Borenich A, Stauber R, Aigner E, Mangge H. Gender-Specific Bile Acid Profiles in Non-Alcoholic Fatty Liver Disease Nutrients. 2024 Jan 13;16(2):250.
8: Czuba B, Vessey DA. The effect of bile acid structure on the activity of bile acid-CoA:glycine/taurine-N-acetyltransferase J Biol Chem. 1982 Aug 10;257(15):8761-5.
9: Yamamoto S, Sato I, Fujii M, Kakimoto M, Honma K, Akiyama N, Sakai M, Fukuhama N, Kumazaki S, Hirohata S, Kitamori K, Yamori Y, Watanabe S. Increased Glycine-conjugated and Unconjugated Bile Acid Levels Associated with Aggravation of Nonalcoholic Steatohepatitis and Cardiovascular Disease in SHRSP5/Dmcr Rat Acta Med Okayama. 2023 Feb;77(1):29-36.
10: Kirilenko BM, Hagey LR, Barnes S, Falany CN, Hiller M. Evolutionary Analysis of Bile Acid-Conjugating Enzymes Reveals a Complex Duplication and Reciprocal Loss History Genome Biol Evol. 2019 Nov 1;11(11):3256-3268.

Products Related to Glycodehydrocholic Acid (Highly Pure) can be found at Chemicals

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in

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