Girard′s Reagent T


Catalog Number: B2012908 (10 g)
Girard′s Reagent T is a high quality reagent that reacts with aldehydes and ketones containing α-dicarbonyl functional groups. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2012908 Category: Tag:


Girard′s Reagent T
Catalog number: B2012908
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 g
Molecular Weight or Concentration: 167.6 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: RT
Keywords: (Carboxymethyl)trimethylammonium chloride hydrazide, (Hydrazinocarbonylmethyl)trimethylammonium chloride, Acethydrazide trimethylammonium chloride
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Lawrence GD, Rahmat R, Makahleh A, Saad B. Liquid Chromatographic Analysis of α-Dicarbonyls Using Girard-T Reagent Derivatives J Chromatogr Sci. 2017 Nov 1;55(10):1043-1050.
2: Lamont L, Hadavi D, Bowman AP, Flinders B, Cooper-Shepherd D, Palmer M, Jordens J, Mengerink Y, Honing M, Langridge J, Siegel TP, Vreeken RJ, Heeren RMA. High-Resolution Ion Mobility Spectrometry Mass Spectrometry for Isomeric Separation of Prostanoids after Girard’s reagent T Derivatization Rapid Commun Mass Spectrom. 2022 Nov 22:e9439.
3: Kiousi P, Fragkaki AG, Kioukia-Fougia N, Angelis YS. Liquid chromatography-mass spectrometry behavior of Girard’s reagent T derivatives of oxosteroid intact phase II metabolites for doping control purposes Drug Test Anal. 2021 Nov;13(11-12):1822-1834.
4: Zhang Y, Wang B, Jin W, Wen Y, Nan L, Yang M, Liu R, Zhu Y, Wang C, Huang L, Song X, Wang Z. Sensitive and robust MALDI-TOF-MS glycomics analysis enabled by Girard’s reagent T on-target derivatization (GTOD) of reducing glycans Anal Chim Acta. 2019 Feb 7;1048:105-114.
5: Miller ID, Kohlhagen MC, Ladwig PM, Dasari S, Kumar S, Dispenzieri A, Willrich MAV, Murray DL. Characterizing M-protein light chain glycosylation via mass spectrometry Clin Biochem. 2022 Nov-Dec;109-110:11-16.
6: Pedrosa JFS, Rasteiro MG, Neto CP, Ferreira PJT. Effect of cationization pretreatment on the properties of cationic Eucalyptus micro/nanofibrillated cellulose Int J Biol Macromol. 2022 Mar 15;201:468-479.
7: Hong H, Wang Y. Derivatization with Girard reagent T combined with LC-MS/MS for the sensitive detection of 5-formyl-2′-deoxyuridine in cellular DNA Anal Chem. 2007 Jan 1;79(1):322-6.
8: Loo JC, Vilim AB, Jordan N, Moffatt J. Application of Girard reagent T to radioimmunological assay of prednisolone in plasma J Pharm Sci. 1976 Mar;65(3):461-2.
9: Langer T, Salamin O, Nicoli R, Grabherr S, Kuuranne T, Musenga A. A comprehensive UHPLC-MS/MS method for the analysis of endogenous and exogenous steroids in serum for anti-doping purposes Drug Test Anal. 2022 Nov;14(11-12):1904-1919.
10: Bogdanov AV, Zaripova IF, Voloshina AD, Sapunova AS, Kulik NV, Voronina JK, Mironov VF. Synthesis and Antimicrobial Study of Novel 1-Benzylated Water-Soluble Isatin-3-hydrazones Chem Biodivers. 2018 Jun;15(6):e1800088.

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