DRAQ5 Fluorescent Probe

Product Description

DRAQ5 Fluorescent Probe
Catalog number: B2019074
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 μL
Molecular Weight or Concentration: 412.49 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: DRAQ5 Fluorescent Probe
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Smith PJ, Darzynkiewicz Z, Errington RJ. Nuclear cytometry and chromatin organization Cytometry A. 2018 Aug;93(8):771-784.
2: Martin RM, Leonhardt H, Cardoso MC. DNA labeling in living cells Cytometry A. 2005 Sep;67(1):45-52.
3: Smith PJ, Blunt N, Wiltshire M, Hoy T, Teesdale-Spittle P, Craven MR, Watson JV, Amos WB, Errington RJ, Patterson LH. Characteristics of a novel deep red/infrared fluorescent cell-permeant DNA probe, DRAQ5, in intact human cells analyzed by flow cytometry, confocal and multiphoton microscopy Cytometry. 2000 Aug 1;40(4):280-91.
4: Richard E, Causse S, Spriet C, Fourré N, Trinel D, Darzacq X, Vandenbunder B, Heliot L. Short exposure to the DNA intercalator DRAQ5 dislocates the transcription machinery and induces cell death Photochem Photobiol. 2011 Jan-Feb;87(1):256-61.
5: Wang Y, Sischka A, Walhorn V, Tönsing K, Anselmetti D. Nanomechanics of Fluorescent DNA Dyes on DNA Investigated by Magnetic Tweezers Biophys J. 2016 Oct 18;111(8):1604-1611.
6: Slaninová I, López-Sánchez N, Šebrlová K, Vymazal O, Frade JM, Táborská E. Introduction of macarpine as a novel cell-permeant DNA dye for live cell imaging and flow cytometry sorting Biol Cell. 2016 Jan;108(1):1-18.
7: Swerts K, Van Roy N, Benoit Y, Laureys G, Philippé J. DRAQ5: improved flow cytometric DNA content analysis and minimal residual disease detection in childhood malignancies Clin Chim Acta. 2007 Apr;379(1-2):154-7.
8: Silva F, Lourenço O, Pina-Vaz C, Rodrigues AG, Queiroz JA, Domingues FC. The use of DRAQ5 to monitor intracellular DNA in Escherichia coli by flow cytometry J Fluoresc. 2010 Jul;20(4):907-14.
9: Errington RJ, Sadiq M, Cosentino L, Wiltshire M, Sadiq O, Sini M, Lizano E, Pujol MD, Morais GR, Pors K. Probing cytochrome P450 bioactivation and fluorescent properties with morpholinyl-tethered anthraquinones Bioorg Med Chem Lett. 2018 May 1;28(8):1274-1277.
https://pubmed.ncbi.nlm.nih.gov/22257116

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