Cholesterol 5α,6α-epoxide

Product Description

Cholesterol 5α,6α-epoxide
Catalog number: B2013606
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 mg
Molecular Weight or Concentration: 402.6 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: RT
Keywords: 5α,6α-Epoxycholestan-3β-ol
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Müller F, Arand M, Frank H, Seidel A, Hinz W, Winkler L, Henle K, Bale E, Beetham JK, Hammock BD, Oesch F. Visualization of a covalent intermediate between microsomal epoxide hydrolase, but not cholesterol epoxide hydrolase, and their substrates Eur J Biochem. 1997 Apr 15;245(2):490-6.
2: Liao PL, Cheng YW, Li CH, Wang YT, Kang JJ. 7-Ketocholesterol and cholesterol-5alpha,6alpha-epoxide induce smooth muscle cell migration and proliferation through the epidermal growth factor receptor/phosphoinositide 3-kinase/Akt signaling pathways Toxicol Lett. 2010 Aug 16;197(2):88-96.
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7: Ferderbar S, Pereira EC, Apolinario E, Bertolami MC, Faludi A, Monte O, Calliari LE, Sales JE, Gagliardi AR, Xavier HT, Abdalla DS. Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus Diabetes Metab Res Rev. 2007 Jan;23(1):35-42.
8: Rakove¡ L. Cholesterol load of microglia: contribution of membrane architecture changes to neurotoxic power? Arch Biochem Biophys. 2013 Sep 1;537(1):91-103.
9: Kamgang Nzekoue F, Henle T, Caprioli G, Sagratini G, Hellwig M. Food Protein Sterylation: Chemical Reactions between Reactive Amino Acids and Sterol Oxidation Products under Food Processing Conditions Foods. 2020 Dec 17;9(12):1882.
10: Mori TA, Croft KD, Puddey IB, Beilin LJ. Analysis of native and oxidized low-density lipoprotein oxysterols using gas chromatography-mass spectrometry with selective ion monitoring Redox Rep. 1996 Feb;2(1):25-34.

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