CCK-Tetrapeptide (30-33)

Product Description

CCK-Tetrapeptide (30-33)
Catalog number: MDP0447
CAS Number: N/A
Sequence: Trp-Met-Asp-Phe-NH2 . HCl . H2O
Amount: 5 mg
Molecular Weight: 596.4 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Koszycki D, Prichard Z, Fiocco AJ, Shlik J, Kennedy JL, Bradwejn J. CCK-B receptor gene and response to cholecystokinin-tetrapeptide in healthy volunteers Peptides. 2012 May;35(1):9-13.
2: Katzman MA, Koszycki D, Bradwejn J. Effects of CCK-tetrapeptide in patients with social phobia and obsessive-compulsive disorder Depress Anxiety. 2004;20(2):51-8.
3: Bradwejn J, Koszycki D, Annable L, Couëtoux du Tertre A, Reines S, Karkanias C. A dose-ranging study of the behavioral and cardiovascular effects of CCK-tetrapeptide in panic disorder Biol Psychiatry. 1992 Nov 15;32(10):903-12.
4: Bourin M, Malinge M, Vasar E, Bradwejn J. Two faces of cholecystokinin: anxiety and schizophrenia Fundam Clin Pharmacol. 1996;10(2):116-26.
5: Shiosaki K, Lin CW, Kopecka H, Craig R, Wagenaar FL, Bianchi B, Miller T, Witte D, Nadzan AM. Development of CCK-tetrapeptide analogues as potent and selective CCK-A receptor agonists J Med Chem. 1990 Nov;33(11):2950-2.
6: Chang HY, Kapás L. Selective activation of CCK-B receptors does not induce sleep and does not affect EEG slow-wave activity and brain temperature in rats Physiol Behav. 1997 Jul;62(1):175-9.
7: Rex A, Barth T, Voigt JP, Domeney AM, Fink H. Effects of cholecystokinin tetrapeptide and sulfated cholecystokinin octapeptide in rat models of anxiety Neurosci Lett. 1994 May 19;172(1-2):139-42.
8: Bradwejn J. Neurobiological investigations into the role of cholecystokinin in panic disorder J Psychiatry Neurosci. 1993 Jul;18(4):178-88.
9: Elliott RL, Kopecka H, Tufano MD, Shue YK, Gauri AJ, Lin CW, Bianchi BR, Miller TR, Witte DG, Stashko MA, et al. Novel Asp32-replacement tetrapeptide analogues as potent and selective CCK-A agonists J Med Chem. 1994 May 27;37(11):1562-8.
10: Ströhle A, Holsboer F, Rupprecht R. Increased ACTH concentrations associated with cholecystokinin tetrapeptide-induced panic attacks in patients with panic disorder Neuropsychopharmacology. 2000 Mar;22(3):251-6.

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