4-Aminoantipyrine (4-AA, Biochemistry Grade)


Catalog Number: B2010067 (10 g)
4-Aminoantipyrine 4-AA is a high quality research product used as component for eagent formulation aimed at glucose determination in the presence of phenol and peroxidase. Custom bulk orders of this product are available upon request.

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SKU: B2010067 Category:


4-Aminoantipyrine 4-AA
Catalog number: B2010067
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 g
pH: na
Supplied as: Ready-to-use
Appearance: White Powder
Applications: component for eagent formulation aimed at glucose determination in the presence of phenol and peroxidase.
Storage: Room temperature
Keywords: 4-Amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one, Ampyrone
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

1: Bachmann F, Duthaler U, Rudin D, Krähenbühl S, Haschke M. N-demethylation of
N-methyl-4-aminoantipyrine, the main metabolite of metamizole. Eur J Pharm Sci.
2018 Jul 30;120:172-180.

2: Berno CR, Rós Bde T, da Silveira IO, Coelho HR, Antoniolli AC, Beatriz A, de
Lima DP, Monreal AC, Sousa FG, da Silva Gomes R, Oliveira RJ. 4-Aminoantipyrine
reduces toxic and genotoxic effects of doxorubicin, cisplatin, and
cyclophosphamide in male mice. Mutat Res Genet Toxicol Environ Mutagen. 2016

3: de Melo da Silva L, Gozzi F, Sirés I, Brillas E, de Oliveira SC, Machulek A
Junior. Degradation of 4-aminoantipyrine by electro-oxidation with a boron-doped
diamond anode: Optimization by central composite design, oxidation products and
toxicity. Sci Total Environ. 2018 Aug 1;631-632:1079-1088.

4: Malvar Ddo C, Aguiar FA, Vaz Ade L, Assis DC, de Melo MC, Jabor VA,
Kalapothakis E, Ferreira SH, Clososki GC, de Souza GE. Dipyrone metabolite 4-MAA
induces hypothermia and inhibits PGE2 -dependent and -independent fever while
4-AA only blocks PGE2 -dependent fever. Br J Pharmacol. 2014

5: Ito Y, Tonogai Y, Suzuki H, Ogawa S, Yokoyama T, Hashizume T, Santo H, Tanaka
KI, Nishigaki K, Iwaida M. Improved 4-aminoantipyrine colorimetry for detection
of residual hydrogen peroxide in noodles, fish paste, dried fish, and herring
roe. J Assoc Off Anal Chem. 1981 Nov;64(6):1448-52.

6: dos Santos GG, Dias EV, Teixeira JM, Athie MC, Bonet IJ, Tambeli CH, Parada
CA. The analgesic effect of dipyrone in peripheral tissue involves two different
mechanisms: neuronal K(ATP) channel opening and CB(1) receptor activation. Eur J
Pharmacol. 2014 Oct 15;741:124-31.

7: Gonçalves Dos Santos G, Vieira WF, Vendramini PH, Bassani da Silva B,
Fernandes Magalhães S, Tambeli CH, Parada CA. Dipyrone is locally hydrolyzed to
4-methylaminoantipyrine and its antihyperalgesic effect depends on
CB2 and kappa-opioid receptors activation. Eur J Pharmacol. 2020 May

8: Cîrstea M, Suhaciu G, Cîrje M. Cross immunological reactions between three
haptens of the “”para”” group and 4-aminoantipyrine. Physiologie. 1979 Apr-

9: Gyenge-Szabó Z, Szoboszlai N, Frigyes D, Záray G, Mihucz VG. Monitoring of
four dipyrone metabolites in communal wastewater by solid phase extraction
liquid chromatography electrospray ionization quadrupole time-of-flight mass
spectrometry. J Pharm Biomed Anal. 2014 Mar;90:58-63.

Products Related to 4-Aminoantipyrine 4-AA : Biochemical Buffers and Solutions

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