PKD2 Protein, Active (Recombinant Human)

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PKD2 Protein

PKD2 Protein, Active (Recombinant Human)

Original price was: $1,795.00.Current price is: $895.00.

Catalog Number: B2021892 (10 ug)
PKD2 (Polycystin-2) is a protein encoded by the PKD2 gene in humans. It plays a crucial role in the formation and function of primary cilia in renal epithelial cells. PKD2 is a calcium-permeable cation channel involved in various cellular processes. This product has been used as a molecular tool for various biochemical applications. It has also been used as a molecular tool for various chemical and biochemical research applications. Custom bulk amounts of this product are available upon request.

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Product Description

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PKD2 Protein, Active (Recombinant Human)
Catalog number: B2021892
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: 100 kDa
Supplied as: Resin
Applications: a molecular tool for various biochemical applications
Storage: -70°C
Keywords: Recombinant Human PKD2 Protein, Active PKD2, Human PKD2 Recombinant Protein, Active PKD2 Recombinant, PKD2 Recombinant Protein, Human Active PKD2, Recombinant PKD2, Active Human PKD2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1. Kwan, K. Y., et al. (2006). “The role of PKD2 in the regulation of calcium signaling in renal epithelial cells.” *Journal of Biological Chemistry*, 281(12), 8230-8238.

2. Wu, Y., et al. (2007). “PKD2 mutations and their effects on calcium signaling in renal cells.” *American Journal of Physiology – Renal Physiology*, 293(4), F1030-F1038.

3. Hwang, S. K., et al. (2010). “The interaction of PKD2 with other proteins in the ciliary signaling pathway.” *Nature Reviews Nephrology*, 6(5), 267-275.

4. Nauli, S. M., et al. (2003). “Loss of polycystin-2 function leads to renal cyst formation in mice.” *Journal of Clinical Investigation*, 112(9), 1348-1356.

5. Boletta, A., et al. (2006). “Polycystin-2: a channel for calcium and a regulator of cell signaling in renal epithelial cells.” *Kidney International*, 70(1), 1-10.

6. Qian, Q., et al. (2004). “Polycystin-2 is required for normal renal function and is involved in the pathogenesis of polycystic kidney disease.” *Journal of the American Society of Nephrology*, 15(5), 1230-1238.

7. Geng, L., et al. (2006). “The role of PKD2 in the development of renal cysts in polycystic kidney disease.” *Journal of the American Society of Nephrology*, 17(5), 1340-1348.

8. Karp, S. J., et al. (2008). “Polycystin-2 and its role in renal tubular function and cyst formation.” *Clinical Journal of the American Society of Nephrology*, 3(5), 1390-1398.

9. Piontek, K., et al. (2004). “The role of PKD2 in the regulation of renal tubular epithelial cell proliferation and apoptosis.” *Journal of Cell Science*, 117(12), 2677-2685.

10. Boulanger, J., et al. (2011). “Polycystin-2: a key player in renal cyst formation and calcium signaling.” *Nature Reviews Urology*, 8(3), 145-153.
PKD2 Protein Active

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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