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7-Alkynyl-Fucose (Highly Pure)

Original price was: $895.00.Current price is: $450.00.

Catalog number: MDP0885 (0.1 mg)
7-Alkynyl-Fucose is a derivative of fucose used as a high sensitivity research imaging probe in research as well as other applications in cellular biology. It has a molecular weight of 356.32 g/mol and is supplied as an amorphous white powder. Custom bulk orders of this product are available upon request.

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Product Description

5/5 - (4 votes)

7-Alkynyl-Fucose
Catalog number: MDP0885
Name: 1,2,3,4-Tetra-O-acetyl-6,7,8-trideoxy-L-galacto-oct-7-ynopyranose
Other name(s): 7-Alkynyl-Fucose
Molecular Formula: C16H20O9
Molecular Mass: 356.32
CAS #: 1193251-95-4
Storage Temperature: -20 C

Indication for Use:
This product if for Research Use Only (RUO). This product is not for administration to humans or animals. This product is not for human or veterinary diagnostic or therapeutic use.

References

1: Kizuka Y, Funayama S, Shogomori H, Nakano M, Nakajima K, Oka R, Kitazume S,
Yamaguchi Y, Sano M, Korekane H, Hsu TL, Lee HY, Wong CH, Taniguchi N. High-
Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker
Discovery. Cell Chem Biol. 2016 Jul 21;23(7):782-792.

2: Valverde P, Vendeville JB, Hollingsworth K, Mattey AP, Keenan T, Chidwick H,
Ledru H, Huonnic K, Huang K, Light ME, Turner N, Jiménez-Barbero J, Galan MC,
Fascione MA, Flitsch S, Turnbull WB, Linclau B. Chemoenzymatic synthesis of
3-deoxy-3-fluoro-l-fucose and its enzymatic incorporation into glycoconjugates.
Chem Commun (Camb). 2020 Jun 11;56(47):6408-6411.

3: Matsumura K, Higashida K, Ishida H, Hata Y, Yamamoto K, Shigeta M, Mizuno-
Horikawa Y, Wang X, Miyoshi E, Gu J, Taniguchi N. Carbohydrate binding
specificity of a fucose-specific lectin from Aspergillus oryzae: a novel probe
for core fucose. J Biol Chem. 2007 May 25;282(21):15700-8.

4: Vardar-Unlü G, McSharry C, Douglas LJ. Fucose-specific adhesins on germ tubes
of Candida albicans. FEMS Immunol Med Microbiol. 1998 Jan;20(1):55-67.

5: Antonik PM, Volkov AN, Broder UN, Re DL, van Nuland NA, Crowley PB. Anomer-
Specific Recognition and Dynamics in a Fucose-Binding Lectin. Biochemistry. 2016
Mar 1;55(8):1195-203.

6: Soroko M, Kwan DH. Enzymatic Synthesis of a Fluorogenic Reporter Substrate
and the Development of a High-Throughput Assay for Fucosyltransferase VIII
Provide a Toolkit to Probe and Inhibit Core Fucosylation. Biochemistry. 2020 Jun
9;59(22):2100-2110.

7: Singh S, Pal K, Yadav J, Tang H, Partyka K, Kletter D, Hsueh P, Ensink E, Kc
B, Hostetter G, Xu HE, Bern M, Smith DF, Mehta AS, Brand R, Melcher K, Haab BB.
Upregulation of glycans containing 3′ fucose in a subset of pancreatic cancers
uncovered using fusion-tagged lectins. J Proteome Res. 2015 Jun
5;14(6):2594-605.

8: Li J, Hsu HC, Mountz JD, Allen JG. Unmasking Fucosylation: from Cell Adhesion
to Immune System Regulation and Diseases. Cell Chem Biol. 2018 May
17;25(5):499-512.

9: Cai D, Xun C, Tang F, Tian X, Yang L, Ding K, Li W, Le Z, Huang W.
Glycoconjugate probes containing a core-fucosylated N-glycan trisaccharide for
fucose lectin identification and purification. Carbohydr Res. 2017 Sep
8;449:143-152.

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (4 votes)

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