Thyroxine-Binding Globulin Conjugated to Alkaline Phosphatase


Catalog Number: B2010743 (10 ug)
Thyroxine-Binding Globulin (TBG) Conjugated to Alkaline Phosphatase is a highly pure recombinant human Thyroxine-Binding Globulin (expressed in HEK293 cells) and conjugated to Alkaline Phosphatase. This product has been used as multipurpose conjugate for various Thyroxine applications. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2010743 Categories: , Tag:


Thyroxine-Binding Globulin (TBG) Conjugated to Alkaline Phosphatase
Catalog number: B2010743
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: na
Supplied as: Solution
Applications: multipurpose conjugate for various Thyroxine biochemical and immunological applications
Storage: -20C
Keywords: TBG-ALP, TBG-AP, TBG Alkaline Phosphatase
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Beg MA, Sheikh IA. Endocrine disruption: Molecular interactions of environmental bisphenol contaminants with thyroid hormone receptor and thyroxine-binding globulin Toxicol Ind Health. 2020 May;36(5):322-335.
2: Schussler GC. Thyroxine-binding globulin: specificity for the hormonally active conformation of triiodothyronine Science. 1972 Oct 13;178(4057):172-4.
3: Pappa T, Ferrara AM, Refetoff S. Inherited defects of thyroxine-binding proteins Best Pract Res Clin Endocrinol Metab. 2015 Oct;29(5):735-47.
4: Hengeveld RCC, Albersen M, Hadders MAH, Hellinga I, Bikker H, Heijboer AC, Paul van Trotsenburg AS, Hillebrand JJ, Boelen A, Zwaveling-Soonawala N. A Newborn Falsely Suspected of Congenital Hypothyroidism due to Mutated Thyroxine-Binding Globulin with Low Binding Affinity Horm Res Paediatr. 2021;94(1-2):76-80.
5: Torkington P, Harrison RJ, Maclagan NF, Burston D. Familial thyroxine-binding globulin deficiency Br Med J. 1970 Jul 4;3(5713):27-9.
6: Hillier AP. Human thyroxine-binding globulin and thyroxine-binding pre-albumin: dissociation rates J Physiol. 1971 Sep;217(3):625-34.
7: Hale TI, Jucker A. Thyroxine-binding-globulin concentration Lancet. 1978 Apr 1;1(8066):725.
8: Korcek L, Tabachnick M. Thyroxine-protein interactions. Interaction of thyroxine and triiodothyronine with human thyroxine-binding globulin J Biol Chem. 1976 Jun 25;251(12):3558-62.
9: Neto EC, Rubin R. Thyroxine-binding globulin in neonates and children West J Med. 2001 Nov;175(5):306.
10: Petruk AA, Labanda MS, Alvarez RM, Marti MA. The allosteric modulation of thyroxine-binding globulin affinity is entropy driven Biochim Biophys Acta. 2013 Jun;1830(6):3570-7.

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