Sialyl 6-sulfo Lewis X Antibody

Description

Sialyl 6-sulfo Lewis X Antibody
Catalog number: B2011026
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: na
Supplied as: Liquid
Applications: molecular tool for various chemical, biochemical and immunological applications
Storage: -20°C
Keywords: Anti- Sialyl 6-sulfo Lewis X Monoclonal Antibody, Anti Sialyl 6-sulfo Lewis X Monoclonal Antibody
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Kroezen BS, Conti G, Girardi B, Cramer J, Jiang X, Rabbani S, Müller J, Kokot M, Luisoni E, Ricklin D, Schwardt O, Ernst B. A Potent Mimetic of the Siglec-8 Ligand 6′-Sulfo-Sialyl Lewis(x) ChemMedChem. 2020 Sep 16;15(18):1706-1719.
2: Taga M, Hoshino H, Low S, Imamura Y, Ito H, Yokoyama O, Kobayashi M. A potential role for 6-sulfo sialyl Lewis X in metastasis of bladder urothelial carcinoma Urol Oncol. 2015 Nov;33(11):496.e1-9.
3: Tateno H, Crocker PR, Paulson JC. Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6′-sulfo-sialyl Lewis X as a preferred glycan ligand Glycobiology. 2005 Nov;15(11):1125-35.
4: Mitsuoka C, Sawada-Kasugai M, Ando-Furui K, Izawa M, Nakanishi H, Nakamura S, Ishida H, Kiso M, Kannagi R. Identification of a major carbohydrate capping group of the L-selectin ligand on high endothelial venules in human lymph nodes as 6-sulfo sialyl Lewis X J Biol Chem. 1998 May 1;273(18):11225-33.
5: Ohmori K, Kanda K, Mitsuoka C, Kanamori A, Kurata-Miura K, Sasaki K, Nishi T, Tamatani T, Kannagi R. P- and E-selectins recognize sialyl 6-sulfo Lewis X, the recently identified L-selectin ligand Biochem Biophys Res Commun. 2000 Nov 11;278(1):90-6.
6: Ohmori K, Fukui F, Kiso M, Imai T, Yoshie O, Hasegawa H, Matsushima K, Kannagi R. Identification of cutaneous lymphocyte-associated antigen as sialyl 6-sulfo Lewis X, a selectin ligand expressed on a subset of skin-homing helper memory T cells Blood. 2006 Apr 15;107(8):3197-204.
7: Hudson SA, Bovin NV, Schnaar RL, Crocker PR, Bochner BS. Eosinophil-selective binding and proapoptotic effect in vitro of a synthetic Siglec-8 ligand, polymeric 6′-sulfated sialyl Lewis x J Pharmacol Exp Ther. 2009 Aug;330(2):608-12.
8: Tjew SL, Brown KL, Kannagi R, Johnson P. Expression of N-acetylglucosamine 6-O-sulfotransferases (GlcNAc6STs)-1 and -4 in human monocytes: GlcNAc6ST-1 is implicated in the generation of the 6-sulfo N-acetyllactosamine/Lewis x epitope on CD44 and is induced by TNF-alpha Glycobiology. 2005 Jul;15(7):7C-13C.
9: Mitsuoka C, Kawakami-Kimura N, Kasugai-Sawada M, Hiraiwa N, Toda K, Ishida H, Kiso M, Hasegawa A, Kannagi R. Sulfated sialyl Lewis X, the putative L-selectin ligand, detected on endothelial cells of high endothelial venules by a distinct set of anti-sialyl Lewis X antibodies Biochem Biophys Res Commun. 1997 Jan 23;230(3):546-51.
10: Kuri-Cervantes L, Pampena MB, Betts MR. Phenotypic Characterization of SLe(x)+ and CLA+ CD4+ T Cells STAR Protoc. 2020 Oct 29;1(3):100154.

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