RSK Substrate


Catalog Number: B2013652 (1 mg)
RSK Substrate is a high quality RSK Substrate. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2013652 Categories: , Tag:


RSK Substrate
Catalog number: B2013652
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration:
Supplied as: Lyophilized powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: RSK Substrate
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Roskoski R Jr. Targeting ERK1/2 protein-serine/threonine kinases in human cancers Pharmacol Res. 2019 Apr;142:151-168.
2: Mayor-Ruiz C, Bauer S, Brand M, Kozicka Z, Siklos M, Imrichova H, Kaltheuner IH, Hahn E, Seiler K, Koren A, Petzold G, Fellner M, Bock C, M_ller AC, Zuber J, Geyer M, Thom_ NH, Kubicek S, Winter GE. Rational discovery of molecular glue degraders via scalable chemical profiling Nat Chem Biol. 2020 Nov;16(11):1199-1207.
3: Cargnello M, Roux PP. Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases Microbiol Mol Biol Rev. 2011 Mar;75(1):50-83.
4: Houles T, Roux PP. Defining the role of the RSK isoforms in cancer Semin Cancer Biol. 2018 Feb;48:53-61.
5: Motta M, Pannone L, Pantaleoni F, Bocchinfuso G, Radio FC, Cecchetti S, Ciolfi A, Di Rocco M, Elting MW, Brilstra EH, Boni S, Mazzanti L, Tamburrino F, Walsh L, Payne K, Fernndez-Jan A, Ganapathi M, Chung WK, Grange DK, Dave-Wala A, Reshmi SC, Bartholomew DW, Mouhlas D, Carpentieri G, Bruselles A, Pizzi S, Bellacchio E, Piceci-Sparascio F, Liewski C, Brinkmann J, Waclaw RR, Waisfisz Q, van Gassen K, Wentzensen IM, Morrow MM, lvarez S, Mart_nez-Garc_a M, De Luca A, Memo L, Zampino G, Rossi C, Seri M, Gelb BD, Zenker M, Dallapiccola B, Stella L, Prada CE, Martinelli S, Flex E, Tartaglia M. Enhanced MAPK1 Function Causes a Neurodevelopmental Disorder within the RASopathy Clinical Spectrum Am J Hum Genet. 2020 Sep 3;107(3):499-513.
6: Casalvieri KA, Matheson CJ, Backos DS, Reigan P. Selective Targeting of RSK Isoforms in Cancer Trends Cancer. 2017 Apr;3(4):302-312.
7: Romeo Y, Zhang X, Roux PP. Regulation and function of the RSK family of protein kinases Biochem J. 2012 Jan 15;441(2):553-69.
8: Alexa A, Sok P, Gross F, Albert K, Kobori E, P_ti L, G_gl G, Bento I, Kuang E, Taylor SS, Zhu F, Ciliberto A, Remnyi A. A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host Nat Commun. 2022 Jan 25;13(1):472.
9: Carriere A, Ray H, Blenis J, Roux PP. The RSK factors of activating the Ras/MAPK signaling cascade Front Biosci. 2008 May 1;13:4258-75.
10: Anjum R, Blenis J. The RSK family of kinases: emerging roles in cellular signalling Nat Rev Mol Cell Biol. 2008 Oct;9(10):747-58.

Products Related to RSK Substrate can be found at Substrates

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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