Phospho-beta-catenin Antibody

Product Description

Phospho-beta-catenin Antibody
Catalog number: B2012940
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 uL
Molecular Weight or Concentration: 85.5 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Catenin beta-1 antibody, Beta-catenin antibody, CTNNB1 antibody, CTNNB antibody
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Richardson AI, Yin CC, Cui W, Li N, Medeiros LJ, Li L, Zhang D. p53 and β-Catenin Expression Predict Poorer Prognosis in Patients With Anaplastic Large-Cell Lymphoma Clin Lymphoma Myeloma Leuk. 2019 Jul;19(7):e385-e392.
2: Sakai T, Nishida Y, Hamada S, Koike H, Ikuta K, Ota T, Ishiguro N. Immunohistochemical staining with non-phospho β-catenin as a diagnostic and prognostic tool of COX-2 inhibitor therapy for patients with extra-peritoneal desmoid-type fibromatosis Diagn Pathol. 2017 Aug 29;12(1):66.
3: Pinczewski J, Obeng RC, Slingluff CL Jr, Engelhard VH. Phospho-β-catenin expression in primary and metastatic melanomas and in tumor-free visceral tissues, and associations with expression of PD-L1 and PD-L2 Pathol Res Pract. 2021 Aug;224:153527.
4: Kielhorn E, Provost E, Olsen D, D’Aquila TG, Smith BL, Camp RL, Rimm DL. Tissue microarray-based analysis shows phospho-beta-catenin expression in malignant melanoma is associated with poor outcome Int J Cancer. 2003 Feb 20;103(5):652-6.
5: Park MH, Kim DJ, You ST, Lee CS, Kim HK, Park SM, Shin EY, Kim EG. Phosphorylation of β-catenin at serine 663 regulates its transcriptional activity Biochem Biophys Res Commun. 2012 Mar 16;419(3):543-9.
6: Qu D, Zhang C, Liu Y, Wang L, Wang J, Xiong Y, Gao D. Glial cell line-derived neurotrophic factor promotes β-catenin phosphorylation and nuclear translocation in glioma cells J Neurosurg Sci. 2015 Dec;59(4):429-35. Epub 2014 Nov 25.
7: Abdul AURM, De Silva B, Gary RK. The GSK3 kinase inhibitor lithium produces unexpected hyperphosphorylation of β-catenin, a GSK3 substrate, in human glioblastoma cells Biol Open. 2018 Jan 26;7(1):bio030874.
8: Zhao S, Fu J, Liu X, Wang T, Zhang J, Zhao Y. Activation of Akt/GSK-3beta/beta-catenin signaling pathway is involved in survival of neurons after traumatic brain injury in rats Neurol Res. 2012 May;34(4):400-7.
9: Pustylnik S, Fiorino C, Nabavi N, Zappitelli T, da Silva R, Aubin JE, Harrison RE. EB1 levels are elevated in ascorbic Acid (AA)-stimulated osteoblasts and mediate cell-cell adhesion-induced osteoblast differentiation J Biol Chem. 2013 Jul 26;288(30):22096-110.
10: Fuentealba LC, Eivers E, Geissert D, Taelman V, De Robertis EM. Asymmetric mitosis: Unequal segregation of proteins destined for degradation Proc Natl Acad Sci U S A. 2008 Jun 3;105(22):7732-7.

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