Matrix Metalloproteinases 390 FRET Substrate


Catalog Number: B2011126 (1 mg)
Matrix Metalloproteinases 390 FRET Substrate is a high quality fluorogenic substrate for assaying matrix metalloproteinases. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Matrix Metalloproteinases 390 FRET Substrate
Catalog number: B2011126
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1094 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: 390 MMP FRET Substrate 2
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Chen X, Zaro JL, Shen WC. Fusion protein linkers: property, design and functionality Adv Drug Deliv Rev. 2013 Oct;65(10):1357-69.
2: Kambe Y, Yamaoka T. Initial immune response to a FRET-based MMP sensor-immobilized silk fibroin hydrogel in vivo Acta Biomater. 2021 Aug;130:199-210.
3: Stawarski M, Rutkowska-Wlodarczyk I, Zeug A, Bijata M, Madej H, Kaczmarek L, Wlodarczyk J. Genetically encoded FRET-based biosensor for imaging MMP-9 activity Biomaterials. 2014 Feb;35(5):1402-10.
4: Pahwa S, Bhowmick M, Amar S, Cao J, Strongin AY, Fridman R, Weiss SJ, Fields GB. Characterization and regulation of MT1-MMP cell surface-associated activity Chem Biol Drug Des. 2019 Jun;93(6):1251-1264.
5: Ji X , Xie S , Jiao Y , Zhang X , Sun D , Yang VC , Wang M , He H , Sun L . MT1-MMP activatable fluorogenic probes with enhanced specificity via high-affinity peptide conjugation for tumor imaging Biomater Sci. 2020 Apr 21;8(8):2308-2317.
6: Li SY, Liu LH, Cheng H, Li B, Qiu WX, Zhang XZ. A dual-FRET-based fluorescence probe for the sequential detection of MMP-2 and caspase-3 Chem Commun (Camb). 2015 Oct 4;51(77):14520-3.
7: Fudala R, Rich R, Mukerjee A, Ranjan AP, Vishwanatha JK, Kurdowska AK, Gryczynski Z, Borejdo J, Gryczynski I. Fluorescence detection of MMP-9. II. Ratiometric FRET-based sensing with dually labeled specific peptide Curr Pharm Biotechnol. 2014;14(13):1134-8.
8: Feng R, Guo L, Fang J, Jia Y, Wang X, Wei Q, Yu X. Construction of the FRET Pairs for the Visualization of Mitochondria Membrane Potential in Dual Emission Colors Anal Chem. 2019 Mar 5;91(5):3704-3709.
9: Wang Y, Lin T, Zhang W, Jiang Y, Jin H, He H, Yang VC, Chen Y, Huang Y. A Prodrug-type, MMP-2-targeting Nanoprobe for Tumor Detection and Imaging Theranostics. 2015 Apr 6;5(8):787-95.
10: Wang Z, Wang Y, Jia X, Han Q, Qian Y, Li Q, Xiang J, Wang Q, Hu Z, Wang W. MMP-2-Controlled Transforming Micelles for Heterogeneic Targeting and Programmable Cancer Therapy Theranostics. 2019 Feb 28;9(6):1728-1740.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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