Macrophage Colony-Stimulating Factor (Human)

Description

Macrophage Colony-stimulating Factor (Human)
Catalog number: B2010318
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 10 ug
pH: 7.4 upon reconstitution
Supplied as: Lyophilized Powder
Appearance: Powder
Applications: highly pure Macrophage Colony-stimulating Factor (Human) expressed in CHO. This protein acts as a hematopoietic growth factor with various glycosylation sites that affects the survival and function of macrophages.
Storage: -20C
Keywords: rHuM-CSF; CSF-1; MGI-IM
Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Ushach I, Zlotnik A. Biological role of granulocyte macrophage colony-
stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) on
cells of the myeloid lineage. J Leukoc Biol. 2016 Sep;100(3):481-9.

2: Jin X, Kruth HS. Culture of Macrophage Colony-stimulating Factor
Differentiated Human Monocyte-derived Macrophages. J Vis Exp. 2016 Jun
30;(112):54244.

3: Hume DA, MacDonald KP. Therapeutic applications of macrophage colony-
stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R)
signaling. Blood. 2012 Feb 23;119(8):1810-20.

4: Chockalingam S, Ghosh SS. Macrophage colony stimulating factor and cancer: a
review. Tumour Biol. 2014 Nov;35(11):10635-44.

5: Hua F, Tian Y, Gao Y, Li C, Liu X. Colony‑stimulating factor 1 receptor
inhibition blocks macrophage infiltration and endometrial cancer cell
proliferation. Mol Med Rep. 2019 Apr;19(4):3139-3147.

6: Yang X, Pande S, Scott C, Friesel R. Macrophage colony stimulating factor
pretreatment of bone marrow progenitor cells regulates osteoclast
differentiation based upon the stage of myeloid development. J Cell Biochem.
2019 Aug;120(8):12450-12460.

7: Kumari A, Silakari O, Singh RK. Recent advances in colony stimulating
factor-1 receptor/c-FMS as an emerging target for various therapeutic
implications. Biomed Pharmacother. 2018 Jul;103:662-679.
8: Liu C, Sun W, Zhuo G, Zhang Z. Impacts of macrophage colony-stimulating
factor (M-CSF) on the expression of natriuretic peptide precursor type C (NPPC)
and regulation of meiotic resumption. Gynecol Endocrinol. 2019
Apr;35(4):320-323.

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